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. 2019 Oct 1;10:1224. doi: 10.3389/fphys.2019.01224

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Copyright © 2019 Wang, Zhao, Ajay, Jiao, Zhang, Wang, Gao, Yuan, Liu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nutrient-sensing signal molecules were ameliorated by QDTS. (A) Is a collection of protein bands. (B) Shows the effect of drug intervention on total AMPK protein and the level of p-AMPK thr172/AMPK in the kidney. (C) Shows the effect on the level of mTORC1 ser2448/mTORC1. (D) Indicates the expression of SIRT1 in the kidney. ^∗p < 0.05 and ^∗∗∗p < 0.001: Compared with the model group, respectively; ^###p < 0.001: compared with the normal control group.