Table 2.
Inflammatory parameters of the whole study population and of the two groups separately.
|
All (n = 50) |
HF-rEF (n = 25) |
HF-pEF (n = 25) |
P | |
|---|---|---|---|---|
| TLR2, MFI | 1.58 ± 0.92 | 1.90 ± 0.97 | 1.25 ± 0.76 | 0.011 |
| TLR4, MFI | 3.98 ± 1.56 | 4.54 ± 1.32 | 3.38 ± 1.62 | 0.007 |
| NF-κB | 1.80 ± 0.93 | 2.67 ± 0.60 | 1.07 ± 0.30 | 0.0001 |
| IL-6, pg/ml | 10.6 ± 7.5 | 15.4 ± 7.7 | 6.0 ± 2.8 | 0.0001 |
| IL-8, pg/ml | 20.6 + 10.1 | 22.4 + 12.8 | 18.6 + 6.2 | NS |
| IL-10, pg/ml | 1.8 ± 1.4 | 1.4 ± 0.9 | 2.3 ± 1.7 | 0.023 |
| MCP-1, pg/ml | 451.2 ± 98.1 | 478.8 ± 81.7 | 401.4 ± 94.6 | 0.003 |
| TNF-α, pg/ml | 3.5 ± 0.9 | 3.5 ± 1.2 | 3.5 ± 0.7 | NS |
| hs-CRP, mg/L | 4.0 ± 2.9 | 5.9 ± 2.6 | 1.9 ± 1.2 | 0.0001 |
| Fibrinogen, mg/dl | 316.0 ± 73 | 336 ± 78 | 285 ± 57 | 0.011 |
hsCRP, High-sensitivity C-reactive protein; IL, Interleukin; MCP1, Monocyte Chemoattractant Protein-1; NF-κB, nuclear factor κB; TLR2, toll-like receptor-2; TLR4, toll-like receptor-4; TNF-α, Tumor necrosis factor alpha.