Table 1.
NMOSD (n = 14) |
MSa (n = 12) |
Controls (n = 10) |
P | |
---|---|---|---|---|
Median age, years (IQR) | 54.0 (37.0–63.0) | 55.5 (40.5–63.5) | 44.5 (24–57) | 0.416 |
Female, n (%) | 10 (71) | 7 (58) | 7 (70) | 0.769 |
Presence of serum Ab, n (%) |
NMO-IgG/AQP4: 8 (57) MOG: 1 (7) |
n/a | n/a | |
Median disease duration, years (IQR) | 8 (3.0–11.0) | 13 (7.5–20.5) | n/a | |
Receiving immunosuppressants or immunomodulatory agents, n (%) | 14 (100)b | 5 (42)c | n/a | . |
Abbreviations: Ab, antibody; AQP4, aquaporin 4; IgG: immunoglobulin G; IQR, interquartile range; MOG, myelin oligodendrocyte glycoprotein; MS, multiple sclerosis; NMO, neuromyelitis optica; NMOSD, neuromyelitis optica spectrum disorders; n/a, not applicable or not available; SD, standard deviation.
aEight (67%) MS patients had relapsing remitting MS, two (17%) had secondary progressive MS, and two (17%) had primary progressive MS.