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. 2019 Oct 7;9:14378. doi: 10.1038/s41598-019-50928-0

Table 1.

Comparisons of demographic and clinical characteristics between the patients with NMOSD, patients with MS and healthy controls.

NMOSD
(n = 14)
MSa
(n = 12)
Controls
(n = 10)
P
Median age, years (IQR) 54.0 (37.0–63.0) 55.5 (40.5–63.5) 44.5 (24–57) 0.416
Female, n (%) 10 (71) 7 (58) 7 (70) 0.769
Presence of serum Ab, n (%)

NMO-IgG/AQP4: 8 (57)

MOG: 1 (7)

n/a n/a
Median disease duration, years (IQR) 8 (3.0–11.0) 13 (7.5–20.5) n/a
Receiving immunosuppressants or immunomodulatory agents, n (%) 14 (100)b 5 (42)c n/a .

Abbreviations: Ab, antibody; AQP4, aquaporin 4; IgG: immunoglobulin G; IQR, interquartile range; MOG, myelin oligodendrocyte glycoprotein; MS, multiple sclerosis; NMO, neuromyelitis optica; NMOSD, neuromyelitis optica spectrum disorders; n/a, not applicable or not available; SD, standard deviation.

aEight (67%) MS patients had relapsing remitting MS, two (17%) had secondary progressive MS, and two (17%) had primary progressive MS.