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. 2019 Oct 7;9:14375. doi: 10.1038/s41598-019-50884-9

Figure 3.

Figure 3

Reduction of DNA fragmentation caused by the combination of agents by z.vad.fmk. (A) Elisa-based DNA fragmentation detection in SKBR3 cells treated with 5 nM YM155, 5 μΜ TPGS with or without 20 μΜ z.vad.fmk for 48 hours. (B) Cell cycle analysis and (C) Annexin V/PI staining of SKBR3 cells treated with the combination of 5μΜ TPGS and 10 nM YM155 for 48 hours with or without z.vad.fmk. The results represent the mean ± SEM of three different replicates and are representative of at least three different experiments. *P value < 0.05, **P value < 0.01, ***P value < 0.001.