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. 2019 Sep 30;21(3):276–289. doi: 10.5853/jos.2019.01522

Table 2.

Reviewed variables classified depending on its association with stroke outcome

Stroke outcome (acute and sub-acute) Baseline variable Early outcome variable Genetic factor
Associated Glucose levels or diabetes mellitus Stroke severity rs20417 (located in COX-2 gene)
Blood pressure Type of acute treatment performed
Atrial fibrillation Sever neurological complications (PH-2)
Prior statin treatment Leukocyte levels
Might associated Hyperlipidemia Leukoaraiosis Candidate genes:
Renal dysfunction Stroke etiology CYP
Prior infections PTGIS
Blood platelet counts TBXAS1
Red blood cells or hemoglobin levels P2RY1
ITGB3
Unknown Heart failure Cerebral edema
Prior dementia Gastrointestinal bleeding
Prior disability Dysphagia
No associated Age
Sex
Ethnicity
Body mass index

PH-2, parenchymal hematoma 2; COX-2, cyclooxygenase-2; CYP, cytochrome P450; PTGIS, prostaglandin I2 synthase; TBXAS1, thromboxane A synthase 1; P2RY1, purinergic receptor P2Y1; ITGB3, integrin subunit beta 3.