Figure 3.

LUF7244 shortens APD and suppresses APD prolongation in hiPS‐CMCs. (a) AP recordings in control and after 5‐min incubation with the indicated drug or drug combinations (red) at 10 μM LUF7244 and 30 nM dofetilide. Horizontal bar indicates 1 s. (b) The bar graphs represent changes in normalized APD₉₀ observed with each drug, or drug combination tested (n = 5). Values are shown as mean ± SEM. *P < .05, significantly different from the same drug(s) at 0 min. ^§ P < .05, dofetilide + LUF7244 significantly different from dofetilide