Figure 5.

Conceptual representation of the relative overfeeding commonly resulting from early full feeding during the first days of critical illness. During this phase, the endogenous glucose production (EGP) is increased, covering up to two-thirds of total energy expenditure (TEE—solid black bold line). Full feeding in this phase will results in overfeeding, as the EGP is not attenuated by energy administration (different form healthy): exogenous feeding adds to the EGP resulting in an excessive energy availability, superior to TEE. (Solid black bold line: TEE; grey bold line: adapted endogenous energy production; dotted bold line: early energy administration; thin line: combined endogenous and exogenous energy administration). Reproduced with permission from [1].