1.

结直肠癌患者的临床病理因素（分类变量）与其CAR的关系

Relationships between clinical characteristics (categorical variables) and CAR in patients with colorectal cancer

Valriable	CAR＜0.132(n=89)(72.39%)	CAR≥0.132(n=74)(27.61%)	P
aWBC: white blood cell, bNLR: neutrophil to lymphocyte ratio, cGPS: Glasgow prognostic score. Chi squared test, bold values indicate statistical significance（P＜0.05）.
Age (year)
＜50	38 (42.7%)	13 (17.6%)	0.001
≥50	51 (57.3%)	61 (82.4%)
Gender
Male	55 (61.8%)	51 (68.9%)	0.344
Female	34 (38.2%)	23 (31.1%)
Smoking
Yes	21 (23.6%)	58 (78.4%)	0.765
No	68 (76.4%)	16 (21.6%)
Tumor site
Right hemicolon	23 (25.8%)	19 (25.7%)
Left hemicolon	43 (48.3%)	29 (39.2%)	0.287
Rectum	18 (20.2%)	13 (17.6%)
Rectosigmoid junctions	2 (2.2%)	11 (14.9%)
Transverse colon	3 (3.4%)	2 (2.7%)
WBC count (9×103/mm3)a
＜4.68	26 (29.2%)	6 (8.1%)	＜0.001
≥4.68	61 (68.5%)	68 (91.9%)
Platelet count(9×104/mm3)a
＜267	72 (80.9%)	40 (54.1%)	＜0.001
≥267	17 (19.1%)	34 (45.9%)
NLRb			0.002
＜1.786	36(40.4%)	13 (17.6%)
≥1.786	53(59.6%)	61 (82.4%)
GPSc
0	79 (88.8%)	7 (9.5%)	＜0.001
1	8 (9.0%)	36 (48.6%)
2	2 (2.2%)	31 (41.9%)
TNM Stage
Ⅰ	3 (3.4%)	4 (5.4%)
Ⅱ	66 (74.2%)	33 (44.6%)	0.002
Ⅲ	12 (13.5%)	24 (32.4%)
Ⅳ	8 (9.0%)	13 (17.6%)
Dukes Stage
A	5 (5.6%)	2 (2.7%)	0.072
B	58 (65.3%)	41 (55.4%)
C	26 (29.2%)	31 (41.9%)	0.462
Surgery
Yes	76 (85.4%)	14 (18.9%)
No	13 (14.6%)	60 (81.1%)
Chemotherapy
No	7 (7.9%)	28 (37.8%)	＜0.001
Yes	82 (92.1%)	46 (62.2%)
Chemotherapy method
No	5 (5.6%)	23 (31.1%)
After surgery	66 (74.2%)	32 (43.2%)	0.084
Before surgery	18 (20.2%)	14 (18.9%)
Palliative	0 (%)	5 (6.8%)
Radiotherapy
No	81 (91%)	70 (94.6%)	0.385
Yes	8 (9.0%)	4 (5.4%)