Table 4.
Retinal nerve fiber layer according to optic disc size.
| Characteristics | Subgroups categorized by CSLO | p Values | ||||
|---|---|---|---|---|---|---|
| Large Disc | Regular Disc | Small Disc | Among 3 Groups* | Post Hoc † | ||
| N (eyes) | Region | 39 | 45 | 12 | ||
| RNFL thickness (um) | G | 95.08 ± 11.41 | 92.02 ± 9.35 | 91.00 ± 7.01 | 0.016 | |
| T | 79.00 ± 15.09 | 77.38 ± 17.48 | 89.75 ± 14.44 | 0.023 | 0.019 (2 vs. 3) | |
| TS | 121.97 ± 26.13 | 123.44 ± 26.27 | 134.33 ± 31.28 | 0.378 | ||
| TI | 134.85 ± 20.81 | 134.53 ± 25.12 | 134.75 ± 28.46 | 0.941 | ||
| N | 75.13 ± 15.27 | 69.04 ± 13.85 | 52.75 ± 16.71 | <0.0001 | 0.015 (2 vs. 3), <0.0001 (1 vs. 3) | |
| NS | 114.79 ± 30.86 | 110.80 ± 28.23 | 107.33 ± 27.88 | 0.5089 | ||
| NI | 100.10 ± 23.23 | 96.00 ± 32.66 | 96.50 ± 22.20 | 0.196 | ||
| RNFL classification (WNL/BL/ONL) | G | 28/6/5 | 37/5/3 | 8/1/3 | 0.324 | |
| T | 37/2/0 | 44/0/1 | 12/0/0 | 0.614 | ||
| TS | 24/9/6 | 34/6/5 | 11/0/1 | 0.133 | ||
| TI | 14/15/10 | 25/9/11 | 6/4/2 | 0.379 | ||
| N | 30/4/5 | 31/6/8 | 5/0/7 | 0.026 | ||
| NS | 34/3/2 | 36/8/1 | 9/3/0 | 0.613 | ||
| NI | 29/5/5 | 32/9/4 | 7/3/2 | 0.594 | ||
| Superior peak location (deg) | 79.69 ± 16.26 | 79.76 ± 14.05 | 75.42 ± 10.73 | 0.552 | ||
| Inferior peak location (deg) | 298.92 ± 12.67 | 298.62 ± 12.49 | 286.50 ± 29.61 | 0.303 | ||
| HVF category (WNL/BL/ONL) | 29/5/5 | 33/6/6 | 6/4/2 | 0.317 | ||
| SE (D) | −2.74 ± 3.77 | −2.19 ± 3.27 | −4.28 ± 3.70 | 0.206 | ||
CSLO, confocal scanning laser ophthalmoscopy. RNFL, retinal nerve fiber layer. G, global. T, temporal. TS, superotemporal. NS, superonasal. N, nasal. NI, inferonasal. TI, inferotemporal. WNL, within normal limits. BL, borderline. ONL, outside normal limits. HVF, Humphrey visual field. SE, spherical equivalent. D, diopter. * Among groups 1, 2, and 3: Kruskal-Wallis test. Bold font indicates significant p values (p < 0.05). †Group 1 vs. group 2 or group 1 vs. group 3 or group 2 vs. group 3: Kruskal-Wallis test with Donn’s post-hoc test. The bold font indicates significant p values (p < 0.05).