Table 1.

Relative number of cytokines and proliferation marker Ki67 positive structures in the cleft affected lip epithelium and subepithelial connective tissue.

Factors/Subjects	Ki67	IL-1		IL-4		IL-6		IL-8		IL-10
	E	E	CT	E	CT	E	CT	E	CT	E	CT
1.	++/+++	+/++	+	+++	++	+++	++	++/+++	+++	+++	+++
2.	0/+	+++	++	+++	++	++++	++	+++	+++	+++	+++
3.	0/+	+	++	++	++	+/++	0	0	0	+/++	+
4.	0	0	+/++	+	+	0	++	++	+/++	+	+
5.	++/+++	++	+++	+	+++	++	+++	0	++	++	+++
6.	++	+++	++	++	+++	+++	+++	++	++	+++	++
7.	++	+++	++	+++	+++	+++	+++	+++	+++	+++	++
8.	++/+++	+++	++	+++	+++	+++	+++	+/++	++	+++	++
9.	+++	+++	++	+++	+++	+++	+++	0	++	+++	++
10.	++/+++	++++	++	+++	+++	+++	+++	0	+	++++	+++
11.	0/+	+/++	++	+	+	+/++	++	0/+	++/+++	++	++
12.	++	+++	++	+++	+	+++	+++	++	++	+++	++
13.	0/+	++	++	0	+	+/++	++	0	+	++	++
14.	++	+++	+++	+++	+++	++/+++	+++	0/+	+++	++/++	+++
15.	++	++	++	++	++	++	++	+/++	+++	++	++
16.	+/++	+++	++	+++	++	++	+++	+/++	+++	++	+/++
Subjects common	++ *	++/+++ *	++	Var ++/+++	++ *	+++	+++	Var +-+++ *	++/+++	++/+++ *	++ *
Control	0	+	++	++	+	+/++	++	+/++	++	+	+

Abbreviations: E—epithelium; CT—connective tissue; Ki67—proliferation marker; IL-1—interleukin 1; IL-4—interleukin 4; IL-6—interleukin 6; IL-8—interleukin 8; IL-10—interleukin 10; 0/+—occasional positive structures, +—few positive structures, +/++—few to moderate number of positive structures, ++—moderate number of positive structures, ++/+++—moderate to numerous positive structures, +++—numerous positive cells, +++/++++—numerous to abundant structures, ++++—abundance of positive structures in the visual field; Var—variable appearance of positive structures; * statistically significant difference of the relative number in structures between the subjects and controls.