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Cytotoxic activity of compounds 1–10 (IC50: μg/mL).
| Compd | KB | Hep-G2 | Lu-1 | MCF-7 |
|---|---|---|---|---|
| 1 | 59.7 | 32.0 | 80.0 | 71.7 |
| 2 | 118.4 | >128 | >128 | >128 |
| 3 | >128 | >128 | >128 | >128 |
| 4 | 4.8 | 2.27 | 4.0 | 14.5 |
| 5 | 2.0 | 2.0 | 4.8 | 11.8 |
| 6 | 47.3 | 78.4 | 71.5 | 60.0 |
| 7 | >128 | 56.0 | >128 | >128 |
| 8 | >128 | >128 | >128 | >128 |
| 9 | >128 | >128 | >128 | >128 |
| Ellipticine | 0.3 ± 0.05 | 0.3 ± 0.05 | 0.4 ± 0.05 | 0.5 ± 0.05 |
