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. 2019 Sep 1;7(9):305. doi: 10.3390/microorganisms7090305

Figure 1.

Figure 1

Histologic characteristics of Epstein-Barr virus-associated gastric carcinoma (EBVaGC). (a) Histology of carcinoma with lymphoid stroma (CLS). Undifferentiated adenocarcinomas (black arrows) are surrounded by infiltrating lymphocytes (white arrows). (H&E staining); (b) EBV-encoded small ribonucleic acid 1 in situ hybridization (EBER-1 ISH). Signals of EBER-1 are observed in nuclei of the carcinoma cells indicated by black arrows in (a). Infiltrating lymphocytes in the stroma indicated by white arrows in (a) are EBER-1 negative. Magnification (a) and (b)(×100).