Table 1.
CD | UC | CG | P Value | |||
---|---|---|---|---|---|---|
N | 100 | 98 | 41 | CD vs. UC | CD vs. CG | UC vs. CG |
Age (years) | 35.59 ± 12.79 | 39.46 ± 14.69 | 30.37 ± 8.58 | ns. | ns | 0.001 |
Body weight (kg) | 63.39 ± 13.71 | 68.38 ± 14.83 | 74.63 ± 14.07 | 0.032 | 0.001 | ns |
Height (cm) | 171.17 ± 10.19 | 171.01 ± 9.25 | 173.05 ± 9.25 | ns | ns | ns |
BMI (kg/m2) | 21.51 ± 3.72 | 23.29 ± 4.28 | 24.79 ± 3.51 | 0.004 | <0.001 | ns |
Vit. D (ng/mL) | 21.14 ± 11.73 | 21.74 ± 8.87 | 21.34 ± 8.94 | ns | ns | ns |
Ca (mmol/L) | 2.32 ± 0.19 | 2.36 ± 0.14 | 2.37 ± 0.08 | ns | ns | ns |
P (mmol/L) | 1.13 ± 0.26 | 1.11 ± 0.28 | 1.20 ± 0.20 | ns | ns | ns |
L2–L4 BMD (g/cm2) | 1.11 ± 0.18 | 1.16 ± 0.14 | 1.23 ± 0.08 | ns | 0.001 | 0.019 |
L2–L4 T-score | −0.90 ± 1.45 | −0.42 ± 1.15 | 0.12 ± 0.69 | ns | <0.001 | 0.015 |
L2–L4 Z-score | −0.12 ± 1.18 | −0.12 ± 1.18 | 0.09 ± 0.64 | ns | 0.015 | ns |
Femoral neck BMD (g/cm2) | 0.94 ± 0.18 | 0.98 ± 1.18 | 1.08 ± 1.16 | ns | <0.001 | 0.010 |
Femoral neck T-score | −0.64 ± 1.30 | −0.31 ± 1.22 | 0.44 ± 1.02 | ns | <0.001 | 0.003 |
Femoral neck Z-score | −0.25 ± 1.11 | 0.08 ± 1.06 | 0.38 ± 0.97 | ns | 0.006 | ns |
Patients with bone fractures (n) % |
(26) 26% | (29) 29.6% | (0) 0.0% | ns | <0.001 | <0.001 |
Women | CD | UC | CG | P Value | ||
n | 49 | 52 | 20 | CD vs. UC | CD vs. CG | UC vs. CG |
Women with bone fractures (n) % |
(13) 26.5% | (15) 28.8% | n.o. | ns | 0.011 | 0.007 |
BMI (kg/m2) | 21.17 ± 4.04 | 22.10 ± 4.32 | 23.39 ± 3.09 | ns | 0.031 | ns |
L2–L4 BMD (g/cm2) | 1.06 ± 0.17 | 1.17 ± 0.13 | 1.21 ± 0.08 | 0.001 | 0.005 | ns |
L2–L4 T score | −1.17 ± 1.41 | −0.34 ± 1.15 | 0.06 ± 0.65 | 0.002 | 0.004 | ns |
L2–L4 Z score | −0.54 ± 1.26 | 0.13 ± 1.17 | 0.21 ± 0.65 | 0.020 | 0.056 | ns |
Femoral neck BMD (g/cm2) | 0.85 ± 0.15 | 0.93 ± 1.14 | 0.99 ± 0.09 | 0.014 | 0.004 | ns |
Femoral neck T-score | −1.08 ± 1.27 | −0.49 ± 1.11 | 0.08 ± 0.72 | 0.033 | <0.001 | ns |
Femoral neck Z-score | −0.50 ± 1.13 | 0.03 ± 1.00 | 0.20 ± 0.70 | 0.064 | 0.015 | ns |
Men | CD | UC | CG | P Value | ||
n | 51 | 47 | 21 | CD vs. UC | CD vs. CG | UC vs. CG |
Men with bone fractures (n) % |
(13) 25.5% | (14) 29.8% | n.o. | ns | 0.013 | 0.006 |
BMI (kg/m2) | 21.58 ± 3.35 | 24.85 ± 3.83 | 25.27 ± 5.98 | 0.002 | <0.001 | ns |
L2–L4 BMD (g/cm2) | 1.20 ± 0.18 | 1.18 ± 0.14 | 1.27 ± 0.08 | ns | ns | ns |
L2–L4 T score | −0.64 ± 1.45 | −0.51 ± 1.16 | 0.17 ± 0.74 | ns | 0.089 | ns |
L2–L4 Z score | −0.39 ± 1.34 | −0.42 ± 1.13 | −0.27 ± 0.63 | ns | ns | ns |
Femoral neck BMD (g/cm2) | 1.03 ±0.16 | 1.05 ± 0.16 | 1.17 ± 0.16 | ns | 0.016 | 0.040 |
Femoral neck T-score | −0.23 ± 1.19 | −0.11 ± 1.31 | 0.78 ± 1.16 | ns | 0.007 | 0.023 |
Femoral neck Z-score | −0.01 ± 1.05 | 0.21 ± 1.14 | 0.56 ± 1.17 | ns | ns | ns |
Abbreviations: IBD—inflammatory bowel disease, UC—ulcerative colitis, CD—Crohn’s disease, BMD—bone mineral density, CG—control group. Quantitative data were presented as mean with standard deviation. n.o.—not observed, ns—non-significant (only statistically significant or borderline significant results were shown).