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. 2019 Aug 24;8(9):1306. doi: 10.3390/jcm8091306

Table 1.

Characteristics of the investigated groups.

CD UC CG P Value
N 100 98 41 CD vs. UC CD vs. CG UC vs. CG
Age (years) 35.59 ± 12.79 39.46 ± 14.69 30.37 ± 8.58 ns. ns 0.001
Body weight (kg) 63.39 ± 13.71 68.38 ± 14.83 74.63 ± 14.07 0.032 0.001 ns
Height (cm) 171.17 ± 10.19 171.01 ± 9.25 173.05 ± 9.25 ns ns ns
BMI (kg/m2) 21.51 ± 3.72 23.29 ± 4.28 24.79 ± 3.51 0.004 <0.001 ns
Vit. D (ng/mL) 21.14 ± 11.73 21.74 ± 8.87 21.34 ± 8.94 ns ns ns
Ca (mmol/L) 2.32 ± 0.19 2.36 ± 0.14 2.37 ± 0.08 ns ns ns
P (mmol/L) 1.13 ± 0.26 1.11 ± 0.28 1.20 ± 0.20 ns ns ns
L2–L4 BMD (g/cm2) 1.11 ± 0.18 1.16 ± 0.14 1.23 ± 0.08 ns 0.001 0.019
L2–L4 T-score −0.90 ± 1.45 −0.42 ± 1.15 0.12 ± 0.69 ns <0.001 0.015
L2–L4 Z-score −0.12 ± 1.18 −0.12 ± 1.18 0.09 ± 0.64 ns 0.015 ns
Femoral neck BMD (g/cm2) 0.94 ± 0.18 0.98 ± 1.18 1.08 ± 1.16 ns <0.001 0.010
Femoral neck T-score −0.64 ± 1.30 −0.31 ± 1.22 0.44 ± 1.02 ns <0.001 0.003
Femoral neck Z-score −0.25 ± 1.11 0.08 ± 1.06 0.38 ± 0.97 ns 0.006 ns
Patients with bone fractures
(n) %
(26) 26% (29) 29.6% (0) 0.0% ns <0.001 <0.001
Women CD UC CG P Value
n 49 52 20 CD vs. UC CD vs. CG UC vs. CG
Women with bone fractures
(n) %
(13) 26.5% (15) 28.8% n.o. ns 0.011 0.007
BMI (kg/m2) 21.17 ± 4.04 22.10 ± 4.32 23.39 ± 3.09 ns 0.031 ns
L2–L4 BMD (g/cm2) 1.06 ± 0.17 1.17 ± 0.13 1.21 ± 0.08 0.001 0.005 ns
L2–L4 T score −1.17 ± 1.41 −0.34 ± 1.15 0.06 ± 0.65 0.002 0.004 ns
L2–L4 Z score −0.54 ± 1.26 0.13 ± 1.17 0.21 ± 0.65 0.020 0.056 ns
Femoral neck BMD (g/cm2) 0.85 ± 0.15 0.93 ± 1.14 0.99 ± 0.09 0.014 0.004 ns
Femoral neck T-score −1.08 ± 1.27 −0.49 ± 1.11 0.08 ± 0.72 0.033 <0.001 ns
Femoral neck Z-score −0.50 ± 1.13 0.03 ± 1.00 0.20 ± 0.70 0.064 0.015 ns
Men CD UC CG P Value
n 51 47 21 CD vs. UC CD vs. CG UC vs. CG
Men with bone fractures
(n) %
(13) 25.5% (14) 29.8% n.o. ns 0.013 0.006
BMI (kg/m2) 21.58 ± 3.35 24.85 ± 3.83 25.27 ± 5.98 0.002 <0.001 ns
L2–L4 BMD (g/cm2) 1.20 ± 0.18 1.18 ± 0.14 1.27 ± 0.08 ns ns ns
L2–L4 T score −0.64 ± 1.45 −0.51 ± 1.16 0.17 ± 0.74 ns 0.089 ns
L2–L4 Z score −0.39 ± 1.34 −0.42 ± 1.13 −0.27 ± 0.63 ns ns ns
Femoral neck BMD (g/cm2) 1.03 ±0.16 1.05 ± 0.16 1.17 ± 0.16 ns 0.016 0.040
Femoral neck T-score −0.23 ± 1.19 −0.11 ± 1.31 0.78 ± 1.16 ns 0.007 0.023
Femoral neck Z-score −0.01 ± 1.05 0.21 ± 1.14 0.56 ± 1.17 ns ns ns

Abbreviations: IBD—inflammatory bowel disease, UC—ulcerative colitis, CD—Crohn’s disease, BMD—bone mineral density, CG—control group. Quantitative data were presented as mean with standard deviation. n.o.—not observed, ns—non-significant (only statistically significant or borderline significant results were shown).