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. 2019 Sep 18;8(9):1483. doi: 10.3390/jcm8091483

Table 1.

Characteristics of the included studies.

First Author/Year Study Design CHD Types Imaging Modality Segmentation Software Utility
* Lau et al. 2018 [2] Cross-sectional DORV with sub-aortic VSD CTA Mimics Accuracy, pre-operative planning, communication, medical education
* Ma et al. 2015 [5] Case series ToF, ToF with ASD, ToF with PDA CTA Philips EBW Comp-Cardiac post-processing software Accuracy, intraoperative orientation, impact on patients’ outcomes a
* Riesenkampff et al. 2009 [6] Case series DORV, VSD, LVOTO, CoA, RVOTO, AVSD, pulmonary atresia, pulmonary stenosis, TGA, congenitally corrected TGA CTA/CMR Medical Imaging and Interaction Toolkit Pre-operative planning
* Schmauss et al. 2015 [7] Case series subpulmonary VSD, HLHS, pulmonary atresia and hypoplastic right ventricle, aortic stenosis CTA/CMR Amira, MeVisLab-Environment Pre-operative planning, intraoperative orientation, pre-surgical simulation
* Shiraishi et al. 2009 [8] Case series CoA, DORV, VSD, HLHS CTA NR Pre-operative planning, pre-surgical simulation
* Valverde et al. 2017 [9] Prospective case-crossover DORV, Complex TGA, univentricle, VSD, criss-cross heart, LVOTO, discordant AV and VA connections CTA/CMR ITK Snap Accuracy, pre-operative planning, communication, medical education
* Bhatla et al. 2017 [10] Case series Complex muscular VSD, DORV CTA/CMR Mimics Pre-operative planning
* Ejaz et al. 2013 [16] RCT NR CTA Advance Workstation (GE Health Systems), Mimics Medical education, pre-operative planning
* Garekar et al. 2016 [17] Case series DORV with remote VSD CTA/CMR NR Pre-operative planning
* Hoashi et al. 2018 [18] Case series DORV, TGA, congenitally corrected TGA, interrupted aortic arch Type B, ToF and MAPCA, HLHS, functional single ventricle, mitral stenosis, AVSD CTA NR Pre-operative planning, pre-surgical simulation
* Loke et al. 2017 [19] RCT Unrepaired ToF, repaired ToF CTA/CMR/echocardiography Mimics Medical education
* McGovern et al. 2017 [20] Case series univentricular heart, abnormal systemic or pulmonary venous drainage, dextrocardia, TGA, HLHS CTA Mimics Pre-operative planning
* Ngan et al. 2006 [21] Case series VSD, pulmonary atresia, MAPCA CTA Mimics Pre-operative planning
* Olejnik et al. 2017 [22] Case series interrupted aortic arch type A with aortopulmonary window type 2, dextroversion, DORV with subaortic VSD, CoA, ToF CTA 3D Slicer Accuracy, pre-operative planning
* Olivieri et al. 2015 [23] Case series VSD echocardiography Mimics Accuracy
* Olivieri et al. 2016 [24] Cross-sectional HLHS with total anomalous pulmonary venous connection, supravalvar aortic stenosis, DORV with hypoplastic and stenotic aortic valve and hypoplastic aortic arch, aortic regurgitation, right partial anomalous pulmonary venous connection, left pulmonary artery sling, RVOTO, truncal valve regurgitation, double aortic arch, TGA with VSD and pulmonary atresia CTA/CMR Mimics Medical education
* Parimi et al. 2018 [25] Case series HLHS post Glenn shunt, CoA, ToF with MAPCAs, pulmonary atresia Rotational angiography Osirix Accuracy
* Ryan et al. 2018 [26] Case control study pulmonary atresia, ToF, DORV, truncus arteriosus, single ventricle CTA/CMR Mimics Pre-operative planning, impact on patients’ outcomes
* Su et al. 2018 [27] RCT 3 different subtypes of VSD CTA NR Medical education
* Wang et al. 2017 [28] RCT VSD, pulmonary atresia, MAPCA CTA Mimics Medical education
* White et al. 2018 [29] RCT 3 different subtypes of VSD, ToF NR Philips IntelliSpace Portal Medical education
* Zhao et al. 2018 [30] Cross-sectional DORV CTA Mimics Accuracy, pre-operative planning, impact on patients’ outcomes
* Biglino et al. 2017a [4] Pre-post study ToF, TGA, CoA, pulmonary atresia, aortic stenosis with dilated ascending aorta, DORV, Ebstein’s anomaly CMR Simpleware Communication
Biglino et al. 2015a [11] RCT CoA, pulmonary atresia, ToF, TGA, aortic stenosis, bicuspid aortic valve, total anomalous pulmonary venous drainage, double-inlet left ventricle CMR Mimics Communication
Biglino et al. 2015b [12] Cross-sectional TGA, ToF, pulmonary atresia, CoA, HLHS, TCPC CMR Mimics Pre-operative planning, medical education, communication
Biglino et al. 2017b [13] Cross-sectional repaired TGA, CoA, ToF, pulmonary atresia with intact ventricular septum, palliated HLHS CMR NR Medical education
* Costello et al.2015 [15] Pre-post study 5 different subtypes of VSD CMR Mimics Medical education
Costello et al. 2014 [14] Pre-post study 5 different subtypes of VSD CMR Mimics Medical education

* = articles that were included in the review. a patients’ outcome includes length of cardiopulmonary bypass time, aortic cross-clamp time, mechanical ventilation time, duration of the surgery, patients’ readmission rate, length of hospitalization, and mortality rate. 3DPHM, three-dimensional printed heart models; AV, atrio-ventricular; AVSD, atrio-ventricular septal defect; ASD, atrial septal defect; CHD, congenital heart disease; CMR, cardiac magnetic resonance; CoA, coarctation of aorta; CTA, computed tomography angiography; DORV, double outlet right ventricle; HLHS, hypoplastic left heart syndrome; LVOTO, left ventricular outflow tract obstruction; MAPCA, major aortopulmonary collateral arteries; NR, not reported; PDA, patent ductus arteriosus; RCT, randomized controlled trial; RVOTO, right ventricular outflow tract obstruction; SVC, superior vena cava; TCPC, total cavopulmonary connection; TGA, transposition of great arteries; ToF, Tetralogy of Fallot; VA, ventriculoarterial; VSD, ventricular septal defect.