Figure 1.

Vasculogenic mimicry (VM) formation defined by CD31−/PAS+ expression is uncommon in patient-derived colorectal cancer (CRC) tissues. (a) Image of a surgical specimen obtained from a human CRC patient. Cubic-shaped tissues of 10 × 5 × 5 mm were resected from normal-appearing tissue and cancerous lesions. The samples were sectioned and used accordingly. (b) Images of HE-staining (left) and CD31/PAS expression (right) in CRC tissues. Arrows indicate CD31+/PAS+ capillary vessels, but not VM formation. Scale bars represent 50 μm. (b) VM quantification in five CRC tissue samples. Data: Averages ± standard deviations.