Table 2.
Description of cachectic, pre-cachectic, and non-cachectic patients.
| Cachectic (n = 16) |
Pre-Cachectic (n = 13) |
Non-Cachectic (n = 23) |
p-Value | |
|---|---|---|---|---|
| Age at surgery + | 58.38 (±10.33) | 55.84 (±11.67) | 62.74 (±12.22) | 0.21 + |
| BMI 1 (kg/m2) | ||||
| at Baseline 2,+ | 25.60 (±2.71) | 29.39 (±3.35) | 26.48 (±4.26) | 0.02 + |
| 6 Months afterwards 3,+ | 23.37 (±3.08) | 28.11 (±3.42) | 26.54 (±4.41) | 0.004 + |
| Weight Change (kg) + | −7.12 (±3.63) | −2.54 (±1.27) | 2.78 (±2.68) | <0.001 + |
| Weight Change (%) | −0.09 (±0.05) | −0.02 (±0.02) | 0.03 (±0.03) | <0.001 + |
| Sex | 0.33 ++ | |||
| Male | 11 (69%) | 11 (85%) | 14 (61%) | |
| Female | 5 (31%) | 2 (15%) | 9 (39%) | |
| Stage | 0.11 ++ | |||
| I | 5 (31%) | 2 (15%) | 7 (30%) | |
| II | 1 (6%) | 5 (38%) | 9 (40%) | |
| III | 6 (38%) | 4 (31%) | 7 (30%) | |
| IV | 4 (25%) | 2 (15%) | 0 | |
| Site | 0.58 ++ | |||
| Colon | 6 (38%) | 5 (38%) | 12 (52%) | |
| Rectal | 10 (62%) | 8 (62%) | 11(48%) | |
| Adjuvant Therapy | 0.14 ++ | |||
| Yes | 10 (62%) | 8 (62%) | 7 (30%) | |
| No | 6 (38%) | 5 (38%) | 16 (70%) | |
| Neo-Adjuvant Therapy | 0.43 ++ | |||
| Yes | 6 (38%) | 4 (31%) | 6 (26%) | |
| No | 10 (62%) | 9 (70%) | 17 (74%) |
1 BMI = body mass index; 2 Baseline as first assessment, either pre-surgery or at 6-month follow-up; 3 follow-up at 6 months after pre-surgery assessment or at 6-month follow-up. + One-way ANOVA was used to compare mean differences across the three different phenotypes for continuous variables. ++ Pearson’s Chi-square test was used to test for distribution differences in categorical variables across the three different phenotypes.