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. 2019 Aug 28;55(9):544. doi: 10.3390/medicina55090544

Table 1.

Main characteristic of herbal derivatives used to alleviate menopause symptoms.

Herbal Derivatives
Scientific Name Common Name Effects Side Effects References
Actaea racemosa Black cohosh Treatment of menopause symptoms such as hot flash, insomnia, irritability, but also musculoskeletal pain, fever, cough. Gastrointestinal discomfort. [76,77]
Evening Primrose Oil Oenothera biennis oil Treatment for menopausal and premenstrual symptoms, but also for atopic dermatitis and rheumatoid arthritis. Gastrointestinal disorders and interaction with antiepilectic drugs. [79,80]
Foeniculum vulgare Fennel Treatment of hot flashes, anxiety, and vaginal atrophy. No side effects reported. [81,82,83]
Ginkgo biloba Ginkgo Treatment of attention disorders in postmenopausal women. Gastrointestinal disorders, allergic reactions, headache, and lowering of seizure threshold. [84,85]
Glycyrrhiza glabra Licorice Treatment of hot flash duration. Cardiovascular disease, hypercortisolism, hypokalemia, and hypernatremia. [86,87]
Hypericum perforatum St. John’s Wort Treatment for the vasomotor symptoms of postmenopausal women. Gastrointestinal disease, sensitivity to light, fatigue. [88,89,90,91]
Medicago sativa Alfalfa Effect on neurovegetative menopausal symptoms. Possible infection with Salmonella, Escherichia coli, and Listeria. [92,93,94,95]
Melissa officinalis Lemon balm, bee balm or honey balm Effect on anxiety. No side effect reported. [96,98,99,100,101]
Panax ginseng Ginseng Treatment of sleep disorders, depression, and sexual function. Possible effect on endometrial thickness. [102,103,104,105,106]
Passiflora incarnata Passion fruit Treatment of vasomotor symptoms, insomnia, anxiety and dysmenorrhea. No side effect reported. [107,108,109]
Pimpinella anisum Anise Treatment of hot flashes but it also exerts an antiulcer action. No side effects reported. [110,111,112,113]
Salvia officinalis Sage herb Treatment of hot flashes and sweats. Possible interaction with diabetes and blood pressure. [114,115,116]
Trifolium pretense Red clover Treatment of hot flashes and it also exerts a bone preventing loss. No side effects reported. [117,118,119,120]
Trigonella foenum Fenugreek Treatment for hot flashes and osteopenia. No particularly side effects. [121,122]
Valerian officinalis Valerian Useful for hot flashes, anxiety, sleep disorders and dysmenorrhea. No side effects reported. [123,124,125]
Vitex agnus-castus Chaste tree, chasteberry or monk’s pepper Treatment for vasomotor symptoms and sleep diseases. Not reported. [126,127,128]