Table 1.
Coating | Fe@C-NH2/BSA/Str | Fe@C-NH2/Casein/Str | Fe@C-NH2/Gelatin B/Str | ||||||
---|---|---|---|---|---|---|---|---|---|
Group | “Small” | “Medium” | “Large” | “Small” | “Medium” | “Large” | “Small” | “Medium” | “Large” |
Dh, nm | 114–121 | 172–186 | 211–233 | 114–131 | 194–198 | 235–274 | 142–160 | 212–243 | 279–309 |
PdI | 0.188–0.208 | 0.158–0.175 | 0.247–0.258 | 0.178–0.201 | 0.132–0.169 | 0.202–0.243 | 0.211–0.248 | 0.200–0.260 | 0.227–0.257 |
Zeta potential, mv | −24–−25 | −23–−25 | −24–−25 | −25–−27 | −25–−26 | −24–−26 | −10–−12 | −9–−10 | −9–−10 |
Relaxivity, 1/mM−1 × s−1 | 234–265 | 262–322 | 186–230 | 310–354 | 318–340 | 303–345 | 266–306 | 296–377 | 282–324 |
Note: Severe aggregation was observed in the conjugate Fe@C-NH2/Gelatin B/Str synthesized at a streptavidin-to-nanocluster ratio of 10:1 immediately after the synthesis, and this conjugate was excluded from our study.