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. 2019 Jun 12;123(1):23–32. doi: 10.1038/s41437-019-0196-0

Fig. 4.

Fig. 4

a The assembly line model for the biosynthesis of erythromycin in Saccharopolyspora (formerly Streptomyces) erythrea. b, c Details of the domain structure of two of the polyketide synthase proteins. AT, acyl transferase; ACP, acyl carrier protein; KS, ketosynthase; KR, ketoreductase; DH, dehydratase; ER, enoyl reductase. The unshaded domain at the right end of protein 3 in a is the thioesterase. From Figure 8.11 of Hopwood (2007), reproduced by permission of Oxford University Press