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. 2019 Oct 1;26(1):1002–1016. doi: 10.1080/10717544.2019.1669734

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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graphic file with name IDRD_A_1669734_F0007a_C.jpg — (A) The cytotoxicity of Bio-oHA-Hyd-FA carrier in MCF-7 cells and BCSCs. (B (a, b)) The cell viabilities of free Cur, free ICA and free ICA&Cur at 24 h and 48 h in MCF-7 cells, respectively. (C (a, b)) The cell viabilities of Cur-loaded Bio-oHA-Hyd-FA micelles, ICA-loaded Bio-oHA-Hyd-FA micelles and ICA&Cur-loaded Bio-oHA-Hyd-FA micelles at 24 h and 48 h in MCF-7 cells, respectively. (D (a, b)) The cell viabilities of free Cur, free ICA and free ICA&Cur at 24 h and 48 h in BCSCs, respectively. (E (a, b)) The cell viabilities of Cur-loaded Bio-oHA-Hyd-FA micelles, ICA-loaded Bio-oHA-Hyd-FA micelles and ICA&Cur-loaded Bio-oHA-Hyd-FA micelles at 24 h and 48 h in BCSCs, respectively. (*indicates p < .05).

graphic file with name IDRD_A_1669734_F0007b_C.jpg — (A) The cytotoxicity of Bio-oHA-Hyd-FA carrier in MCF-7 cells and BCSCs. (B (a, b)) The cell viabilities of free Cur, free ICA and free ICA&Cur at 24 h and 48 h in MCF-7 cells, respectively. (C (a, b)) The cell viabilities of Cur-loaded Bio-oHA-Hyd-FA micelles, ICA-loaded Bio-oHA-Hyd-FA micelles and ICA&Cur-loaded Bio-oHA-Hyd-FA micelles at 24 h and 48 h in MCF-7 cells, respectively. (D (a, b)) The cell viabilities of free Cur, free ICA and free ICA&Cur at 24 h and 48 h in BCSCs, respectively. (E (a, b)) The cell viabilities of Cur-loaded Bio-oHA-Hyd-FA micelles, ICA-loaded Bio-oHA-Hyd-FA micelles and ICA&Cur-loaded Bio-oHA-Hyd-FA micelles at 24 h and 48 h in BCSCs, respectively. (*indicates p < .05).