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Cytotoxic efficiency of the Mel-alone and 18:1βCDg-Mel complexes (at 2:1 molar ratio) in Mel-resistant A375 melanoma cells. A375 cells were seeded 1.5 × 104 cells/well in 96-well plate and after 24 h treated with Mel-alone and 18:1βCDg-Mel complexes with final Mel concentrations of 30 µM and 80 µM. Cell death was reported as using MTT assay in comparison with nontreated cells. N = 3 ± SD * indicates significant (P < 0.05).
