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Predose (upper) and 100 mg aprepitant postdose (bottom) PET scans in the transverse section at the level of cerebellum (left) and striatum (right) in a human subject. Warmer colours symbolise higher uptake of radiotracer [18F]SPA-RQ. Based on ratio method with cerebellum reference, estimated receptor occupancy by aprepitant for this subject was 94% at 1053 ng/mL of aprepitant in plasma [163].
