Table 2.

The IC₅₀ values determined for SP and various radiobioconjugates based on SP analogues [53].

Substance	IC50 ± SEM [nM]
Substance P	2.7 ± 0.22
111In-DOTAGA-Substance P	1.1
111In-DOTAGA-[Met(O2)11]-Substance P	9.8 ± 1.00
111In-DOTA-[Met(O2)11]-Substance P	3.55 ± 0.45
111In-DOTA-[Sar9]-Substance P	3.20 ± 0.30
111In-DOTA-[Thi8]-Substance P	7.30 ± 2.00
111In-DOTA-[Thi7]-Substance P	9.40 ± 1.60
111In-DOTA-[Sar9,Met(O2)11]-Substance P	2.00 ± 0.00
111In-DOTA-[Thi8,Met(O2)11]-Substance P	0.78 ± 0.03
111In-DOTA-[Thi8,Sar9]-Substance P	3.40 ± 0.40
111In-DOTA-[Thi7,Thi8]-Substance P	7.70 ± 0.70