Table 1.
List of validated siRNAs (Qiagen, MD, USA) that were used in this study.
| siRNA | Target Sequence | Targeted Gene | Validation Cell Line | % knockdown |
|---|---|---|---|---|
| Hs-AKT1-5 | AATCACACCACCTGACCAAGA | AKT (protein kinase B) | HeLa S3 | 90 |
| Hs_MAPK1_l0 | AAGTTCGAGTAGCTATCAAGA | Mitogen-activated protein kinase | HeLa S3 | 90 |
| Hs-ROS1-5 | AAGGTAATTGCTCTAACTTTA | ROS Proto-Oncogene 1, Receptor tyrosine kinase | HeLa | 87 |
| Hs-ERBB2-14 | AACAAAGAAATCTTAGACGAA | Receptor tyrosine-protein kinase ERBB-2 or human epidermal growth factor receptor 2 (HER2) |
MCF-7 | 92 |