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. 2019 Sep 2;11(9):454. doi: 10.3390/pharmaceutics11090454

Table 5.

Protein and mRNA expression in healthy tissue. Data were collected from the Human Protein Atlas (HPA). Protein expression level (P) is indicated with 0, 1, 2 or 3 (dark green, light green, orange and red, respectively) representing no, low, medium or high expression, respectively. mRNA expression (R) is shown as reads per kilo base per million mapped reads (RPKM; dark green representing 0, light green 1–3, orange 4–9 and red >9 RPKM). White boxes: No protein or RNA expression data available from HPA.

GeneSymbol Protein/RNA CXCR4 ADGRG1 LPAR3 PTH2R LGR6 GPR39 ADGRG2 OXTR GABBR1 GeneSymbol Protein/RNA CXCR4 ADGRG1 LPAR3 PTH2R LGR6 GPR39 ADGRG2 OXTR GABBR1
Pituitary Gland P Oral Mucosa P 2 0 1 0 0 0
R 20 6 0 0 11 0 1 0 33 R
Hypothalamus P Esophagus P 2 0 1 1 0 0
R 8 18 1 1 3 0 0 3 72 R 9 15 4 0 3 0 0 1 13
Cerebral Cortex P 1 1 2 1 0 2 Stomach P 2 1 1 0 0 0
R 3 21 2 2 0 0 0 1 88 R 14 14 0 0 0 2 2 0 17
Hippocampus P 0 0 1 2 0 2 Duodenum P 3 0 3 0 0 0
R 6 16 2 1 0 0 0 1 56 R
Caudate P 0 0 0 3 0 1 Small Intestine P 3 0 2 0 0 0
R 5 22 1 0 0 0 0 3 91 R 151 6 0 0 1 1 1 0 19
Cerebellum P 0 0 0 1 0 2 Colon P 3 1 3 0 0 0
R 1 6 0 0 3 0 0 1 111 R 11 6 0 0 1 1 0 0 26
Thyroid Gland P 2 0 2 0 0 1 Rectum P 3 0 2 0 0 0
R 19 48 0 0 4 0 1 0 28 R
Parathyroid Gland P 3 0 2 0 0 1 Kidney P 2 3 2 1 0 1
R R 16 53 0 2 1 1 1 0 15
Adrenal Gland P 2 0 1 1 0 1 Urinary Bladder P 2 0 2 0 0 1
R 45 4 1 0 0 0 0 0 16 R 18 14 3 0 2 2 1 0 27
Appendix P 2 0 3 0 0 0 Testis P 2 0 2 0 0 1
R R 3 23 7 0 7 2 1 0 11
Bone Marrow P 3 0 1 1 0 0 Prostate P 2 0 2 1 0 0
R R 16 14 7 0 4 0 3 1 41
Lymph Node P 2 0 0 1 0 0 Epididymis P 2 0 1 0 2 1
R R
Tonsil P 2 0 2 1 0 0 Seminal Vesicle P 2 0 2 0 0 1
R R
Spleen P 0 0 0 0 0 0 Fallopian Tube P 2 0 1 0 0 1
R 214 3 0 0 5 0 1 0 42 R 19 9 2 0 4 0 5 0 45
Heart Muscle P 1 0 2 1 0 1 Breast P 1 0 3 1 0 1
R 5 4 4 0 3 0 0 0 13 R 18 17 0 0 4 0 2 15 26
Skeletal Muscle P 1 1 2 0 0 1 Vagina P 1 0 0 0 0 0
R 1 2 0 0 0 0 0 0 3 R 16 14 4 0 3 0 1 0 37
Smooth Muscle P 1 0 0 0 0 1 Cervix, Uterine P 2 0 1 1 0 1
R R 11 10 2 0 3 0 1 0 45
Lung P 1 0 2 1 0 1 Endometrium P 1 0 2 1 0 1
R 57 13 1 0 2 1 1 0 23 R 8 7 0 0 1 0 0 3 47
Nasopharynx P 2 0 2 0 1 Ovary P 1 0 1 0 0 0
R R 5 2 1 0 1 0 0 1 49
Bronchus P 3 0 2 0 0 1 Placenta P 2 0 2 1 0 1
R R
Liver P 2 0 2 0 0 0 Soft Tissue P 1 0 0 1 0 1
R 6 1 0 0 1 1 0 0 3 R
Gall Bladder P 2 0 3 0 0 0 Adipose Tissue P
R R 21 13 0 0 1 0 2 0 20
Pancreas P 2 3 2 0 0 0 Skin P 2 0 2 1 0 1
R 3 11 3 0 0 1 0 0 6 R 5 27 3 0 3 0 0 0 17
Salivary Gland P 2 0 2 0 0 0 Sum RNA 748 442 51 7 72 12 26 30 1057
R 14 23 3 1 1 0 2 0 17 Sum Protein n/a 78 n/a 10 70 23 2 n/a 31