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. 2019 Oct 7;14:43. doi: 10.1186/s13020-019-0263-8

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effect of TKSE on mitochondrial dysfunction in colorectal cancer cells. a Mitochondrial damage caused by TKSE (50–500 µg/mL) was investigated using rhodamine 123. The left side of the fluorocytogram indicates the percentage of cells showing loss of mitochondrial membrane potential. b Percentage of mitochondrial membrane potential losses in the vehicle-treated controls and TKSE-treated HT-29 cells. c Percentage of mitochondrial membrane potential losses in the vehicle-treated controls and TKSE-treated CT-26 cells. Significance vs. vehicle-treated controls, ***p < 0.001. Rh123; rhodamine 123