Table 4.
Univariate analysis of risk factors for OS in BCR-ABL1 positive ALL
| Group | Numbers | OS (range, month) | P value |
|---|---|---|---|
| Leukocyte count, 109/L | 0.736 | ||
| ≥ 50 | 21 | 13 (6.5~19.5) | |
| < 50 | 29 | 14 (6.7~21.3) | |
| LDH | 0.775 | ||
| ≥ 250 U/L | 37 | 13.0 (10.7~15.3) | |
| < 250 U/L | 10 | 8.0 (0.0~27.3) | |
| CR + PR | 0.019 | ||
| Yes | 44 | 19.0 (12.7~25.2) | |
| No | 5 | 7.0 (4.4~9.6) | |
| BCR-ABL1 FISH | 0.006 | ||
| Complex signal patterns | 36 | 5.0 (2.4~7.6) | |
| single patterns | 16 | 15.0 (8.3~21.7) | |
| Cytogenetic abnormalities | 0.001 | ||
| t (9;22) | 11 | 27 (14.5~39.5) | |
| ACAs | 11 | 6 (1.7~10.3) |
Abbreviations: LDH lactic dehydrogenase, CR complete remission, PR partial remission