Table 1.
Association between CyclinD1/DICER expression and clinicopathologic characteristics
| Characteristics | Numbers of Patients | CyclinD1 | P value | DICER | P value | ||
|---|---|---|---|---|---|---|---|
| Low expression | High expression | Low expression | High expression | ||||
| Age (years) | 0.066 | 0.129 | |||||
| ≤ 55 | 21 | 15 | 6 | 17 | 4 | ||
| > 55 | 12 | 8 | 4 | 6 | 6 | ||
| Gender | 0.295 | 0.142 | |||||
| Male | 19 | 10 | 9 | 12 | 7 | ||
| Female | 14 | 8 | 6 | 10 | 4 | ||
| Pathology grade | < 0.001* | < 0.001 | |||||
| Low (I-II) | 8 | 2 | 6 | 7 | 1 | ||
| High (III-IV) | 25 | 9 | 16 | 22 | 3 | ||
| TNM stage | 0.002* | < 0.001 | |||||
| I | 4 | 2 | 2 | 4 | 0 | ||
| II | 8 | 2 | 6 | 6 | 2 | ||
| III | 11 | 4 | 7 | 10 | 1 | ||
| IV | 10 | 3 | 7 | 8 | 2 | ||
| Lymph node metastasis | 0.225 | 0.265 | |||||
| Negative | 13 | 7 | 6 | 7 | 6 | ||
| Positive | 20 | 11 | 9 | 13 | 7 | ||
| Distant metastasis | 0.560 | < 0.05 | |||||
| M0 | 16 | 8 | 8 | 9 | 7 | ||
| M1 | 17 | 10 | 7 | 13 | 4 | ||
Low expression: IHC staining index≤6; High expression: IHC staining index> 6