Table III.
Demographics of the included patients and results of univariate analysis.
| A, Non-surgery vs. surgery group | ||||
|---|---|---|---|---|
| Features | NP | NE | NEE | P-value |
| Age, years | 0.341 | |||
| <40 | 3 | 2 | 2.02 | |
| ≥40, <50 | 22 | 10 | 12.62 | |
| ≥50, <60 | 114 | 51 | 60.07 | |
| ≥60, <70 | 214 | 91 | 98.62 | |
| ≥70, <80 | 178 | 92 | 79.70 | |
| ≥80, <90 | 53 | 28 | 21.19 | |
| ≥90, <100 | 4 | 2 | 1.78 | |
| Sex | 0.714 | |||
| Male | 252 | 118 | 120.99 | |
| Female | 336 | 158 | 155.01 | |
| Race | 0.279 | |||
| Hispanic | 15 | 5 | 7.69 | |
| AI/AN | 2 | 0 | 0.09 | |
| API | 12 | 7 | 5.15 | |
| African descent | 52 | 17 | 27.18 | |
| Caucasian | 506 | 247 | 235.81 | |
| Unknown | 1 | 0 | 0.09 | |
| Histology | 0.678 | |||
| SCC, NOS | 462 | 222 | 213.83 | |
| OCC | 11 | 5 | 5.69 | |
| SCC, IC | 4 | 2 | 2.89 | |
| CSCC | 111 | 47 | 53.59 | |
| Grade (8) | 0.149 | |||
| I | 10 | 2 | 3.93 | |
| II | 23 | 7 | 14.32 | |
| III | 281 | 127 | 125.92 | |
| IV | 274 | 140 | 131.83 | |
| T (8) | 0.135 | |||
| T1a | 189 | 86 | 92.83 | |
| T1b | 128 | 60 | 63.02 | |
| T2a | 173 | 77 | 79.92 | |
| T2b | 29 | 19 | 10.54 | |
| T3 | 53 | 25 | 21.82 | |
| T4 | 16 | 9 | 7.86 | |
| N (8) | 0.007 | |||
| 0 | 360 | 150 | 176.48 | |
| 1 | 105 | 54 | 45.92 | |
| 2 | 116 | 69 | 51.28 | |
| 3 | 7 | 3 | 2.33 | |
| Stage (8) | 0.003 | |||
| IA | 190 | 77 | 99.00 | |
| IB | 112 | 44 | 53.56 | |
| IIA | 108 | 56 | 45.88 | |
| IIB | 31 | 13 | 13.80 | |
| IIIA | 135 | 80 | 57.93 | |
| IIIB | 12 | 6 | 5.84 | |
| Surgery | <0.001 | |||
| No | 294 | 161 | 125.40 | |
| Yes | 294 | 115 | 150.60 | |
| B, Sublobectomy vs. lobe/s group | ||||
| Features | NP | NE | NEE | P-value |
| Age, years | 0.384 | |||
| <40 | N/A | N/A | N/A | |
| ≥40, <50 | 2 | 2 | 0.79 | |
| ≥50, <60 | 28 | 9 | 13.77 | |
| ≥60, <70 | 61 | 22 | 21.40 | |
| ≥70, <80 | 57 | 25 | 23.78 | |
| ≥80, <90 | 20 | 8 | 6.26 | |
| ≥90, <100 | N/A | N/A | N/A | |
| Sex | 0.586 | |||
| Male | 56 | 25 | 22.92 | |
| Female | 112 | 41 | 43.08 | |
| Race | 0.979 | |||
| Hispanic | 2 | 1 | 0.70 | |
| AI/AN | N/A | N/A | N/A | |
| API | N/A | N/A | N/A | |
| African descent | 8 | 4 | 4.17 | |
| Caucasian | 157 | 61 | 61.07 | |
| Unknown | 1 | 0 | 0.06 | |
| Histology | 0.743 | |||
| SCC, NOS | 144 | 57 | 55.32 | |
| OCC | 1 | 0 | 0.36 | |
| SCC, IC | N/A | N/A | N/A | |
| CSCC | 23 | 9 | 10.31 | |
| Grade (8) | 0.355 | |||
| I | 4 | 0 | 1.38 | |
| II | 5 | 1 | 2.54 | |
| III | 72 | 27 | 29.03 | |
| IV | 87 | 38 | 33.05 | |
| T (8) | 0.258 | |||
| T1a | 85 | 29 | 37.15 | |
| T1b | 27 | 11 | 11.03 | |
| T2a | 36 | 15 | 11.00 | |
| T2b | 2 | 2 | 0.85 | |
| T3 | 12 | 6 | 3.82 | |
| T4 | 6 | 3 | 2.15 | |
| N (8) | <0.001 | |||
| 0 | 108 | 33 | 46.06 | |
| 1 | 23 | 12 | 6.44 | |
| 2 | 35 | 19 | 13.11 | |
| 3 | 2 | 2 | 0.39 | |
| Stage (8) | 0.006 | |||
| IA | 70 | 21 | 32.86 | |
| IB | 25 | 6 | 8.97 | |
| IIA | 22 | 12 | 6.30 | |
| IIB | 8 | 3 | 2.76 | |
| IIIA | 39 | 21 | 13.51 | |
| IIIB | 4 | 3 | 1.60 | |
| Surgery | 0.049 | |||
| No | 84 | 26 | 33.90 | |
| Yes | 84 | 40 | 32.10 | |
| C, Lobe/s vs. pneumonectomy group | ||||
| Feature | NP | NE | NEE | P-value |
| Age, years | 0.210 | |||
| <40 | – | – | – | |
| ≥40, <50 | 2 | 1 | 1.27 | |
| ≥50, <60 | 4 | 1 | 0.85 | |
| ≥60, <70 | 10 | 8 | 4.75 | |
| ≥70, <80 | 3 | 0 | 2.44 | |
| ≥80, <90 | 1 | 0 | 0.68 | |
| ≥90, <100 | N/A | N/A | N/A | |
| Sex | 0.544 | |||
| Male | 6 | 3 | 3.91 | |
| Female | 14 | 7 | 6.09 | |
| Race | 0.632 | |||
| Hispanic | 1 | 0 | 0.68 | |
| AI/AN | 1 | 0 | <0.001 | |
| API | 1 | 1 | 0.31 | |
| African descent | 4 | 2 | 1.68 | |
| Caucasian | 13 | 7 | 7.33 | |
| Unknown | N/A | N/A | N/A | |
| Histology | 0.235 | |||
| SCC, NOS | 7 | 2 | 3.62 | |
| OCC | N/A | N/A | N/A | |
| SCC, IC | 1 | 0 | 0.88 | |
| CSCC | 12 | 8 | 5.50 | |
| Grade (8) | 0.438 | |||
| I | 1 | 1 | 0.31 | |
| II | 4 | 2 | 2.83 | |
| III | 8 | 3 | 3.97 | |
| IV | 7 | 4 | 2.90 | |
| T (8) | 0.113 | |||
| T1a | 1 | 0 | 0.88 | |
| T1b | N/A | N/A | N/A | |
| T2a | 5 | 2 | 3.14 | |
| T2b | 2 | 1 | 0.17 | |
| T3 | 8 | 4 | 4.28 | |
| T4 | 4 | 3 | 1.52 | |
| N (8) | 0.710 | |||
| 0 | 6 | 2 | 3.09 | |
| 1 | 9 | 5 | 4.59 | |
| 2 | 5 | 3 | 2.32 | |
| 3 | N/A | N/A | N/A | |
| Stage (8) | 0.650 | |||
| IA | 1 | 0 | 0.88 | |
| IB | 2 | 1 | 1.27 | |
| IIA | 3 | 1 | 1.19 | |
| IIB | 1 | 0 | 0.88 | |
| IIIA | 12 | 7 | 5.30 | |
| IIIB | 1 | 1 | 0.48 | |
| Surgery | 0.185 | |||
| No | 10 | 6 | 4.02 | |
| Yes | 10 | 4 | 5.98 | |
Lobe/s, lobectomy or bilobectomy; NP, Number of Patients; NE, Number of Events; NEE, Number of Expected Events; AI/AN, American Indian/Alaska Native; API, Asian or Pacific Islander; SCC, Small cell carcinoma; OCC, Oat cell carcinoma; IC, Intermediate cell; CSCC, Combined small cell carcinoma; N/A, No observation in the database.