Table V.
Survival functions of clinicopathological features stratified by surgery.
| A. Non-surgery vs. surgery group | |||||
|---|---|---|---|---|---|
| Non-surgery | Surgery | ||||
| Feature | NE | NEE | NE | NEE | P-value |
| Age, years | <0.01 | ||||
| <40 | 2 | 2.0 | NT | NT | NS |
| ≥40, <50 | 6 | 6.2 | 4 | 3.8 | 0.91 |
| ≥50, <60 | 33 | 20.8 | 18 | 30.2 | <0.01 |
| ≥60, <70 | 46 | 39.6 | 45 | 51.4 | 0.17 |
| ≥70, <80 | 53 | 39.8 | 39 | 52.2 | <0.01 |
| ≥80, <90 | 19 | 15.5 | 9 | 12.5 | 0.17 |
| ≥90, <100 | 2 | 2.0 | NT | NT | NS |
| Sex | <0.01 | ||||
| Male | 65 | 54.0 | 53 | 64.0 | 0.04 |
| Female | 96 | 71.3 | 62 | 86.7 | <0.01 |
| Race | <0.01 | ||||
| Hispanic | 2 | 1.9 | 3 | 3.1 | 0.89 |
| AI/AN | NT | NT | NT | NT | NS |
| API | 3 | 3.1 | 4 | 3.9 | 0.91 |
| African descent | 9 | 8.1 | 8 | 8.9 | 0.66 |
| Caucasian | 147 | 111.3 | 100 | 135.7 | <0.01 |
| Histology | <0.01 | ||||
| SCC, NOS | 139 | 113.5 | 83 | 108.5 | <0.01 |
| OCC | 5 | 4.2 | 0 | 0.8 | 0.29 |
| SCC, IC | 2 | 0.8 | 0 | 1.2 | 0.09 |
| CSCC | 15 | 9.7 | 32 | 37.3 | 0.05 |
| Grade (8) | <0.01 | ||||
| I | 1 | 0.5 | 1 | 1.5 | 0.37 |
| II | 3 | 2.0 | 4 | 5.0 | 0.42 |
| III | 77 | 55.6 | 50 | 71.4 | <0.01 |
| IV | 80 | 69.5 | 60 | 70.5 | 0.07 |
| T (8) | <0.01 | ||||
| T1a | 56 | 34.5 | 30 | 51.5 | <0.01 |
| T1b | 42 | 36.8 | 18 | 23.2 | 0.16 |
| T2a | 38 | 29.7 | 39 | 47.4 | 0.05 |
| T2b | 15 | 15.1 | 4 | 3.9 | 0.96 |
| T3 | 7 | 9.1 | 18 | 15.9 | 0.36 |
| T4 | 3 | 2.5 | 6 | 6.5 | 0.68 |
| N (8) | <0.01 | ||||
| 0 | 100 | 68.6 | 50 | 81.4 | <0.01 |
| 1 | 22 | 24.3 | 32 | 29.7 | 0.49 |
| 2 | 38 | 32.2 | 31 | 36.8 | 0.15 |
| 3 | 1 | 1.8 | 2 | 1.2 | 0.31 |
| Stage (8) | <0.01 | ||||
| IA | 50 | 31.1 | 27 | 45.9 | <0.01 |
| IB | 31 | 20.8 | 13 | 23.2 | <0.01 |
| IIA | 32 | 32.0 | 24 | 24.0 | 1.00 |
| IIB | 7 | 7.2 | 6 | 5.9 | 0.93 |
| IIIA | 39 | 33.5 | 41 | 46.5 | 0.20 |
| IIIB | 2 | 2.7 | 4 | 3.3 | 0.58 |
| B, Sublobectomy vs. lobe/s group | |||||
| Sub-lobectomy | lobe/s | ||||
| Feature | NE | NEE | NE | NEE | P-value |
| Age, years | 0.05 | ||||
| <40 | N/A | N/A | N/A | N/A | NS |
| ≥40, <50 | 2 | 2.0 | NT | NT | NS |
| ≥50, <60 | 5 | 5.5 | 4 | 3.5 | 0.75 |
| ≥60, <70 | 12 | 9.6 | 10 | 12.4 | 0.30 |
| ≥70, <80 | 14 | 11.3 | 11 | 13.7 | 0.28 |
| ≥80, <90 | 7 | 4.0 | 1 | 4.1 | 0.03 |
| ≥90, <100 | N/A | N/A | N/A | N/A | NS |
| Sex | 0.06 | ||||
| Male | 17 | 14.9 | 8 | 10.1 | 0.38 |
| Female | 23 | 17.7 | 18 | 23.3 | 0.09 |
| Race | 0.05 | ||||
| Hispanic | 1 | 1.0 | NT | NT | NS |
| AI/AN | N/A | N/A | N/A | N/A | N/A |
| API | N/A | N/A | N/A | N/A | NS |
| African descent | 3 | 2.8 | 1 | 1.2 | 0.81 |
| Caucasian | 36 | 28.4 | 25 | 32.6 | 0.05 |
| Histology | 0.04 | ||||
| SCC, NOS | 32 | 25.1 | 25 | 31.9 | 0.06 |
| OCC | NT | NT | NT | NT | NS |
| SCC, IC | N/A | N/A | N/A | N/A | NS |
| CSCC | 8 | 6.8 | 1 | 2.2 | 0.36 |
| Grade (8) | 0.06 | ||||
| I | NT | NT | NT | NT | NS |
| II | 1 | 1.0 | 0 | 0.0 | 1.00 |
| III | 18 | 14.5 | 9 | 12.5 | 0.17 |
| IV | 21 | 17.0 | 17 | 21.0 | 0.19 |
| T (8) | 0.07 | ||||
| T1a | 14 | 10.7 | 7 | 10.4 | 0.52 |
| T1b | 5 | 3.5 | 1 | 2.5 | 0.48 |
| T2a | 5 | 1.0 | 7 | 11.0 | 0.22 |
| T2b | 1 | 0.6 | 2 | 2.4 | 0.32 |
| T3 | 12 | 12.6 | 9 | 8.4 | 0.24 |
| T4 | 3 | 3.0 | NT | NT | NS |
| N (8) | 0.02 | ||||
| 0 | 22 | 16.2 | 11 | 16.8 | 0.04 |
| 1 | 5 | 1.2 | 7 | 10.8 | <0.001 |
| 2 | 11 | 12.2 | 8 | 6.8 | 0.56 |
| 3 | 2 | 2.0 | NT | NT | NS |
| Stage (8) | 0.02 | ||||
| IA | 14 | 10.7 | 7 | 10.4 | 0.14 |
| IB | 5 | 3.5 | 1 | 2.5 | 0.20 |
| IIA | 5 | 1.0 | 7 | 11.0 | <0.01 |
| IIB | 1 | 0.6 | 2 | 2.4 | 0.56 |
| IIIA | 12 | 12.6 | 9 | 8.4 | 0.77 |
| IIIB | 3 | 3.0 | NT | NT | NS |
| C, Lobe/s vs. Pneumonectomy group | |||||
| lobe/s | Pneumonec-tomy | ||||
| Feature | NE | NEE | NE | NEE | P-value |
| Age, years | 0.42 | ||||
| <40 | N/A | N/A | N/A | N/A | NS |
| ≥40, <50 | NT | NT | 1 | 1.0 | NS |
| ≥50, <60 | 0 | 0.0 | 1 | 1.0 | 1.00 |
| ≥60, <70 | 6 | 6.7 | 2 | 1.3 | 0.42 |
| ≥70, <80 | NT | NT | NT | NT | NS |
| ≥80, <90 | NT | NT | NT | NT | NS |
| ≥90, <100 | N/A | N/A | N/A | N/A | NS |
| Sex | 0.18 | ||||
| Male | 2 | 1.2 | 1 | 1.9 | 0.3 |
| Female | 4 | 2.8 | 3 | 4.2 | 0.35 |
| Race | 0.24 | ||||
| Hispanic | NT | NT | NT | NT | NS |
| AI/AN | NT | NT | NT | NT | NS |
| API | 1 | 1.0 | N/A | N/A | NS |
| African descent | 1 | 0.5 | 1 | 1.5 | 0.32 |
| Caucasian | 4 | 2.9 | 3 | 4.1 | 0.39 |
| Histology | 0.70 | ||||
| SCC, NOS | 1 | 0.2 | 1 | 1.8 | 0.03 |
| OCC | N/A | N/A | N/A | N/A | NS |
| SCC, IC | NT | NT | NT | NT | NS |
| CSCC | 5 | 5.3 | 3 | 2.7 | 0.80 |
| Grade (8) | 0.20 | ||||
| I | 1 | 1.0 | NT | NT | NS |
| II | 1 | 0.8 | 1 | 1.3 | 0.71 |
| III | 2 | 1.7 | 1 | 1.3 | 0.70 |
| IV | 2 | 0.9 | 2 | 3.1 | 0.14 |
| T (8) | 0.31 | ||||
| T1a | NT | NT | NT | NT | NS |
| T1b | N/A | N/A | N/A | N/A | NS |
| T2a | 1 | 0.2 | 1 | 1.8 | 0.05 |
| T2b | 0 | 0.0 | 1 | 1.0 | 1.00 |
| T3 | 3 | 2.9 | 1 | 1.1 | 0.91 |
| T4 | 2 | 1.7 | 1 | 1.3 | 0.69 |
| N (8) | 0.24 | ||||
| 0 | 0 | 0.5 | 2 | 1.6 | 0.45 |
| 1 | 4 | 2.1 | 1 | 2.9 | 0.06 |
| 2 | 2 | 1.8 | 1 | 1.2 | 0.78 |
| 3 | N/A | N/A | N/A | N/A | NS |
| Stage (8) | 0.48 | ||||
| IA | NT | NT | NT | NT | NS |
| IB | 1 | 1.0 | N/A | N/A | NS |
| IIA | 1 | 0.5 | 0 | 0.5 | 0.32 |
| IIB | NT | NT | NT | NT | NS |
| IIIA | 4 | 3.6 | 3 | 3.4 | 0.74 |
| IIIB | 1 | 1.0 | NT | NT | NS |
Lobe/s, lobectomy or bilobectomy; NP, Number of Patients; NE, Number of Events; NEE, Number of Expected Events; AI/AN, American Indian/Alaska Native; API, Asian or Pacific Islander; SCC, Small cell carcinoma; OCC, Oat cell carcinoma; IC, Intermediate cell; CSCC, Combined small cell carcinoma; NT, No test possible because of no failures observed; N/A, No observation in the database.