Skip to main content
. 2019 Aug 26;11(9):433. doi: 10.3390/pharmaceutics11090433

Figure 3.

Figure 3

Acoustic properties of PBCA microbubbles upon storage. Representative bright mode (B-mode) and contrast mode (C-mode) US images of freshly prepared control PBCA-MB and PBCA-MB stored at 4 °C, 25 °C, and 37 °C for up to 20 weeks (A–D). Quantification of the US images revealed no significant differences in backscatter signals when MB were stored at 4 °C and 25 °C (E,F). For samples stored at 37 °C, the acoustic signals decreased significantly from week 1 onwards (G). Values represent average ± SD of three different batches, measured in triplicates. * and ** indicates p < 0.05 and p < 0.005, respectively.