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. 2019 Sep 19;18(5):5481–5489. doi: 10.3892/ol.2019.10891

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Immunohistochemistry analyses of the chimera of engrafted hCD45 cells in the liver, spleen and lung of OCI-AML3-injected NSG-SGM3 mice. The sections were stained positive for hCD45 (green). The nuclei in the sections were counter-stained with DAPI (blue). (A) Blank control mice (without the injection of OCI-AML3 cells; n=3). (B) Vehicle control mice (treated with DMSO at a concentration of 0.001%; n=3). (C) ABT-737 single-agent (100 mg/kg) treated mice (n=3). (D) A-1210477 single-agent (100 mg/kg) treated mice (n=3). Magnifications, ×200 (liver); ×400 (spleen and lung). hCD45, human CD45.