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. 2019 Sep 5;18(5):4778–4788. doi: 10.3892/ol.2019.10811

Table V.

Association of CTAG2 expression with the clinicopathological features of hepatocellular carcinoma patients from the First Affiliated Hospital of China Medical University.

CTAG2 expression, n (%)


Characteristic Category n Low High P-value
Sex Female   8 5 (62.5) 3 (37.5) 0.361
Male 38 17 (44.7) 21 (55.3)
Age, years <60 34 14 (41.2) 20 (58.8) 0.129
≥60 12 8 (66.7) 4 (33.3)
T stage 1–2 28 16 (57.1) 12 (42.9) 0.056
3–4 15 4 (26.7) 11 (73.3)
HBV status Negative 11 9 (81.8) 2 (18.2) 0.010
Positive 35 13 (37.1) 22 (76.1)
AFP level Low (<upper limit) 18 13 (72.2) 5 (27.8) 0.004
High (≥upper limit) 25 7 (28.0) 18 (72.0)
Differentiation High 17 9 (52.9) 8 (47.1) 0.494
Low 26 11 (42.3) 15 (57.7)
CEA Negative   8 5 (62.5) 3 (37.5) 0.199
Positive 12 4 (33.3) 8 (66.7)
GPC-3 Negative   7 3 (42.9) 4 (57.1) 0.606
Positive 26 14 (53.8) 12 (46.2)

P-value was obtained from Pearson's χ2 test or Fisher's exact test. CTAG2, cancer/testis antigen 2; HBV, hepatitis B virus; AFP, α-fetoprotein; CEA, carcinoembryonic antigen; GPC-3, glypican-3.