Table 2.
Summary statistics for immunoconversions and associations with gastrointestinal symptoms by immunoconversion definition from univariate GEE models
| Pathogen | Immunoconversion definition a | Total N of immunoconversions | N / % of immunoconversions with symptoms b | % of episodes of symptoms with immunoconversion | Unadjusted OR of immunoconversion after an episode of symptoms |
|---|---|---|---|---|---|
| Cryptosporidium | 1 | 63 | 7 / 11.1% | 3.3% | 3.07 (1.42; 6.63)* |
| 2 | 43 | 5 / 11.6% | 2.3% | 3.20 (1.30; 7.87)* | |
| 3 | 32 | 4 / 12.5% | 1.9% | 3.46 (1.23; 9.75)* | |
| GI norovirus | 1 | 182 | 8 / 4.4% | 14.5% | 3.77 (1.02; 14.0)* |
| 2 | 125 | 6 / 4.8% | 10.9% | 3.80 (0.74; 19.6) | |
| 3 | 102 | 4 / 3.9% | 7.3% | 2.67 (0.29; 25.0) | |
| GII noroviruses | 1 | 177 | 7 / 4.0% | 12.7% | 3.42 (1.21; 9.64)* |
| 2 | 112 | 7 / 6.3% | 12.7% | 5.25 (1.76; 15.7)* | |
| 3 | 72 | 3 / 4.2% | 5.5% | 3.58 (0.73; 17.6) | |
| All noroviruses | 1 | 294 | 13 / 4.4% | 23.6% | 4.26 (1.74; 10.5)* |
| 2 | 210 | 13 / 6.2% | 23.6% | 6.15 (2.42; 15.6)* | |
| 3 | 155 | 7 / 4.5% | 12.7% | 3.88 (0.99; 15.2) |
Immunoconversion definitions: (1) Four-fold increase in antibody response between monthly samples; (2) same as in 1 and post-conversion responses above the 80 % prediction bound of spline regression on age; (3) same as in 1 and post-conversion responses above the 90 % prediction bound of spline regression on age.
Symptoms definitions: gastroenteritis (diarrhea or vomiting or abdominal cramps) for Cryptosporidium, combined diarrhea and vomiting symptoms for noroviruses.
p < 0.05