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. 2019 Sep 13;18(5):5043–5054. doi: 10.3892/ol.2019.10866

Table III.

Degree value of ten key genes.

Gene symbol Description Degree Betweenness centrality Closeness centrality
CA2 Carbonic anhydrase 2 44 7.61×10−2 6.80×10−1
GUCA2A Guanylate cyclase activator 2A 35 8.12×10−2 6.80×10−1
CEACAM7 Carcinoembryonic antigen-related cell adhesion molecule 7 34 4.07×10−2 6.30×10−1
MMP7 Matrix metalloproteinase-7 33 4.37×10−2 6.07×10−1
SLC4A4 Solute carrier family 4 member 4 26 2.90×10−2 5.86×10−1
CA12 Carbonic anhydrase 12 25 3.27×10−2 6.14×10−1
GCG Glucagon 25 1.79×10−2 6.00×10−1
MS4A12 Membrane-spanning 4-domains subfamily A member 12 24 1.04×10−2 5.93×10−1
CA1 Carbonic anhydrase 1 24 9.63×10−3 5.93×10−1
CLCA1 Calcium-activated chloride channel regulator 1 24 8.05×10−3 5.73×10−1

CA2, carbonic anhydrase 2; GUCA2A, guanylate cyclase activator 2A; CEACAM7, carcinoembryonic antigen-related cell adhesion molecule 7; MMP7, matrix metalloproteinase-7; SLC4A4, solute carrier family 4 member 4; CA, carbonic anhydrase 12; GCG, glucagon; MS4A12, membrane-spanning 4-domains subfamily A member 12; CLCA1, calcium-activated chloride channel regulator 1.