Table III.

Degree value of ten key genes.

Gene symbol	Description	Degree	Betweenness centrality	Closeness centrality
CA2	Carbonic anhydrase 2	44	7.61×10−2	6.80×10−1
GUCA2A	Guanylate cyclase activator 2A	35	8.12×10−2	6.80×10−1
CEACAM7	Carcinoembryonic antigen-related cell adhesion molecule 7	34	4.07×10−2	6.30×10−1
MMP7	Matrix metalloproteinase-7	33	4.37×10−2	6.07×10−1
SLC4A4	Solute carrier family 4 member 4	26	2.90×10−2	5.86×10−1
CA12	Carbonic anhydrase 12	25	3.27×10−2	6.14×10−1
GCG	Glucagon	25	1.79×10−2	6.00×10−1
MS4A12	Membrane-spanning 4-domains subfamily A member 12	24	1.04×10−2	5.93×10−1
CA1	Carbonic anhydrase 1	24	9.63×10−3	5.93×10−1
CLCA1	Calcium-activated chloride channel regulator 1	24	8.05×10−3	5.73×10−1

CA2, carbonic anhydrase 2; GUCA2A, guanylate cyclase activator 2A; CEACAM7, carcinoembryonic antigen-related cell adhesion molecule 7; MMP7, matrix metalloproteinase-7; SLC4A4, solute carrier family 4 member 4; CA, carbonic anhydrase 12; GCG, glucagon; MS4A12, membrane-spanning 4-domains subfamily A member 12; CLCA1, calcium-activated chloride channel regulator 1.