Table 1.
Demographic table.
| Pathology diagnosis | NL (n = 8) | BL (n = 8) | TCMR (n = 8) | ABMR (n = 8) | PVAN (n = 8) | P-value |
|---|---|---|---|---|---|---|
| Recipient age* (years) | 52.9 ± 13.9 (54.0; 37–74) |
51.8 ± 11.6 (49.5; 40–74) |
48.5 ± 14.9 (46.0; 27–75) |
44.6 ± 14.0 (48.5; 17–58) |
54.3 ± 13.9 (59.0; 32–69) |
0.71 (ns) |
| Gender (%M) | 50.0 | 50.0 | 50.0 | 75.0 | 75.0 | 0.65 (ns) |
| Time post-transplant* (months) | 6.1 ± 0.4 (6.0; 6–7) |
6.6 ± 2.8 (6.0; 2–12) |
7.6 ± 7.5 (6.0; 0.5–24) |
91.6 ± 99.7 (48.0; 0.5–264) |
34.3 ± 40.7 (17.5; 4–102) |
0.004 |
| eGFR# (ml/min/1.73 m2)* | 63.1 ± 12.4 (59.0; 48–87) |
51.5 ± 18.4 (49.0; 27–79) |
50.3 ± 20.7 (51.0; 21–87) |
35.4 ± 23.3 (30.0; 9–69) |
35.6 ± 13.1 (36.0; 21–55) |
0.02 |
| Creatinine (mg/dL)* | 1.2 ± 0.2 (1.1; 0.9–1.5) |
1.5 ± 0.5 (1.6; 0.8–2.1) |
1.6 ± 0.9 (1.3; 0.6–3.3) |
2.8 ± 2.1 (2.0; 1.02–6.62) |
2.1 ± 0.6 (2.1; 1.36–3.06) |
0.04 |
|
Urine protein/Creatinine (mg Pro/mg Cre)* |
0.2 ± 0.0 (0.1; 0.11–0.2) |
0.2 ± 0.0 (0.2; 0.11–0.26) |
0.2 ± 0.2 (0.1; 0.08–0.53) |
3.7 ± 4.6 (2.3; 0.14–14.3) |
0.2 ± 0.1 (0.2; 0.08–0.32) |
0.006 |
| Transplant type (%) | 0.22 (ns) | |||||
| LRRT | 25.0 | 12.5 | 12.5 | 50.0 | 12.5 | |
| LURT | 25.0 | 25.0 | 12.5 | 25.0 | 0.0 | |
| DDRT | 25.0 | 62.5 | 62.5 | 12.5 | 75.0 | |
| SPK | 25.0 | 0.0 | 12.5 | 12.5 | 0.0 | |
| SHK | 0.0 | 0.0 | 0.0 | 0.0 | 12.5 | |
| Recipient race (%) | 0.80 (ns) | |||||
| Caucasian | 50.0 | 50.0 | 25.0 | 50.0 | 50.0 | |
| Hispanic/Latina | 37.5 | 25.0 | 12.5 | 25.0 | 25.0 | |
| Asian | 0.0 | 25.0 | 25.0 | 12.5 | 25.0 | |
| African American | 12.5 | 0.0 | 25.0 | 0.0 | 0.0 | |
| Hawaiian | 0.0 | 0.0 | 12.5 | 0.0 | 0.0 | |
| Other | 0.0 | 0.0 | 0.0 | 12.5 | 0.0 | |
| Native renal disease (%) | 0.61 (ns) | |||||
| Hypertension (HTN) |
25.0 | 12.5 | 25.0 | 0.0 | 0.0 | |
| Glomerulonephritis | 0.0 | 12.5 | 25.0 | 37.5 | 12.5 | |
| Type I diabetes (DBI) |
25.0 | 0.0 | 12.5 | 12.5 | 0.0 | |
| Type II diabetes (DBII) |
12.5 | 25.0 | 12.5 | 0.0 | 25.0 | |
| HTN + DBI/DBII | 12.5 | 0.0 | 0.0 | 0.0 | 12.5 | |
| Unknown | 12.5 | 12.5 | 0.0 | 25.0 | 25.0 | |
| Tubulointerstitial nephritis |
12.5 | 0.0 | 0.0 | 0.0 | 12.5 | |
| Polycystic kidney disease |
0.0 | 37.5 | 12.5 | 25.0 | 12.5 | |
| HIV | 0.0 | 0.0 | 12.5 | 0.0 | 0.0 |
NL, normal graft function; BL, borderline changes; TCMR, T-cell mediated rejection; AMR, antibody mediated rejection; PVAN, polyomavirus; LRRT, living related renal transplant; LURT, living unrelated renal transplant; DDRT, deceased donor renal transplant; SPK, simultaneous pancreas-kidney transplant; SHK, simultaneous heart-kidney transplant.
*
Unit listed: Mean ± SD (Median; Range), P-values for continuous values are calculated with 1 way ANOVA, and for categorical variables with Fisher Exact test.
#
eGFR was calculated with Modification of Diet in Renal Disease (MDRD) Study equation (24).