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. 2019 Sep 10;18(5):4629–4638. doi: 10.3892/ol.2019.10842

Table III.

Effect of SNPs in selected genes on the prognosis in patients with advanced gastric cancer.

Log-rank P-value for PFS Log-rank P-value for OS


Gene SNP Allelic change General Dominant Recessive General Dominant Recessive
KDR rs7692791 T/C 0.032a 0.009a 0.281 0.227 0.093 0.364
rs2305948 C/T 0.619 0.329 0.871 0.277 0.109 0.748
rs6838752 T/C 0.097 0.137 0.053 0.203 0.254 0.095
rs2034965 G/A 0.155 0.065 0.240 0.065 0.031 0.883
rs13109660 G/A 0.795 0.522 0.687 0.365 0.376 0.481
rs1870377 T/A 0.030a 0.008a 0.256 0.091 0.032a 0.250
rs1531290 A/G 0.236 0.128 0.313 0.451 0.845 0.207
NRP-1 rs2070296 G/A 0.498 0.417 0.486 0.993 0.964 0.909
rs2804495 G/T 0.064 0.150 0.028a 0.085 0.308 0.029
rs2065364 G/A 0.052 0.300 0.015a 0.113 0.587 0.037a
PDGFβ rs4821877 C/T 0.712 0.490 0.862 0.949 0.933 0.747
PDGFRα rs6554162 G/A 0.513 0.322 0.751 0.501 0.413 0.561
a

P<0.05. KDR, kinase insert domain receptor; NRP-1, neuropilin-1; PDGF, platelet-derived growth factor; PDGFR, PDGF receptor; OS, overall survival; PFS, progression-free survival; SNP, single nucleotide polymorphism.