Table III.
Log-rank P-value for PFS | Log-rank P-value for OS | |||||||
---|---|---|---|---|---|---|---|---|
Gene | SNP | Allelic change | General | Dominant | Recessive | General | Dominant | Recessive |
KDR | rs7692791 | T/C | 0.032a | 0.009a | 0.281 | 0.227 | 0.093 | 0.364 |
rs2305948 | C/T | 0.619 | 0.329 | 0.871 | 0.277 | 0.109 | 0.748 | |
rs6838752 | T/C | 0.097 | 0.137 | 0.053 | 0.203 | 0.254 | 0.095 | |
rs2034965 | G/A | 0.155 | 0.065 | 0.240 | 0.065 | 0.031 | 0.883 | |
rs13109660 | G/A | 0.795 | 0.522 | 0.687 | 0.365 | 0.376 | 0.481 | |
rs1870377 | T/A | 0.030a | 0.008a | 0.256 | 0.091 | 0.032a | 0.250 | |
rs1531290 | A/G | 0.236 | 0.128 | 0.313 | 0.451 | 0.845 | 0.207 | |
NRP-1 | rs2070296 | G/A | 0.498 | 0.417 | 0.486 | 0.993 | 0.964 | 0.909 |
rs2804495 | G/T | 0.064 | 0.150 | 0.028a | 0.085 | 0.308 | 0.029 | |
rs2065364 | G/A | 0.052 | 0.300 | 0.015a | 0.113 | 0.587 | 0.037a | |
PDGFβ | rs4821877 | C/T | 0.712 | 0.490 | 0.862 | 0.949 | 0.933 | 0.747 |
PDGFRα | rs6554162 | G/A | 0.513 | 0.322 | 0.751 | 0.501 | 0.413 | 0.561 |
P<0.05. KDR, kinase insert domain receptor; NRP-1, neuropilin-1; PDGF, platelet-derived growth factor; PDGFR, PDGF receptor; OS, overall survival; PFS, progression-free survival; SNP, single nucleotide polymorphism.