Table 3.
Mean Dose [Gy] To Thoracic Organs At Risk. Reported Mean Doses Based On Results In42,50,51,53,56 For Early-Stage Mediastinal HL And On Results In24,44,46,54 For Stage I–IV Primary Mediastinal Hodgkin/non-Hodgkin Lymphoma (including Pediatric Patients) Are Normalized To A 30 Gy Prescription Dose And Weighted According To Number Of Patients In Each Publication. Data Do Not Allow For Reporting Of Dosimetric Parameters Other Than Mean Dose
| Heart | Lungs | Breasts | Esophagus | Thyroid | ||
|---|---|---|---|---|---|---|
| Early-stage mediastinal HL | ||||||
| FB-3DCRT | 10.3 | 8.4 | 3.5 | 16.1 | 15.0 | |
| FB-mRT | 8.9 | 10.0 | 5.5 | 16.1 | 19.0 | |
| FB-PT | 7.2 | 6.8 | 1.4 | 13.9 | 15.1 | |
| DIBH-mRT | 3.5 | 7.8 | 4.5 | N/A | N/A | |
| DIBH-PT | 1.6 | 5.6 | 1.6 | N/A | N/A | |
| Stage I–IV mediastinal HL/NHL | ||||||
| FB-3DCRT | 8.3 | 18.8 | 7.4 | N/A | N/A | |
| FB-mRT | 10.1 | 12.1 | 6.8 | 14.0 | 21.3 | |
| FB-PT | 5.9 | 6.0 | 3.0 | 11.2 | 22.3 | |
| DIBH-mRT | 11.4 | 9.4 | 4.4 | 18.0 | 24.4 | |
| DIBH-PT | 7.2 | 5.7 | 2.1 | 14.5 | 22.2 | |
Abbreviations: 3DCRT, 3-dimensional conformal radiotherapy; DIBH, deep inspiration breath-hold; FB, free-breathing; mRT, modern radiotherapy; N/A, not available; PT, proton therapy.