Table I.
Association between the expression levels of IL-2, IL-10, IgG and sIgA, and the IL-2/IL-10 ratio prior to treatment.
| IL-2 | IL-10 | IL-2/IL-10 | sIgA | IgG | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group | HPV (−) | HPV (+) | HPV (−) | HPV (+) | HPV (−) | HPV (+) | HPV (−) | HPV (+) | HPV (−) | HPV (+) |
| Control | 64.35±16.84 | 57.06±21.15 | 30.78±22.41 | 30.19±21.06 | 4.91±5.97 | 8.11±17.36 | 1.67±0.94 | 1.41±0.62 | 2.85±1.57 | 3.12±1.62 |
| LSIL | 63.36±18.67a | 63.59±22.74a | 12.70±8.35a | 13.59±6.52a | 12.72±16.28a | 9.25±14.33a | 1.36±16.69a | 1.02±1.24a | 4.22±4.42 | 3.81±6.29 |
| HSIL | 44.33±16.84a | 45.27±17.15a | 18.85±9.69a | 18.35±8.69a | 4.28±5.54a | 4.45±6.40a | 1.36±1.28a | 1.28±1.15a | 5.52±8.30 | 6.87±8.38 |
| SCC | 70.33±44.22a | 81.92±74.70a | 30.99±24.63a | 47.37±15.36a | 3.74±2.78a | 2.21±2.40a | 1.02±0.55a | 1.46±1.04a | 7.47±8.84 | 6.71±9.80 |
Data are presented as mean ± standard deviation.
a
P-value of the overall two-two comparison, P<0.05 vs. control. IL, interleukin; IgG, immunoglobulin G; sIgA, secretory immunoglobulin A; HPV, human papilloma virus; LSIL, low-grade squamous intraepithelial lesions; HSIL, high-grade squamous intraepithelial lesions; SCC, squamous cell carcinoma.