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. 2019 Sep 6;18(5):4882–4890. doi: 10.3892/ol.2019.10819

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — miR-193b leads to enhanced cell migration and invasion of A172 cells. (A-C) Cell migration and invasion of A172 were promoted by the overexpression of miR-193b, and suppressed by its inhibition, following transfection with miR mimic and inhibitor, respectively. (D) Western blot analysis and (E) quantification of MMP-2 and MMP-9 protein expression in A172 cells following transfection. The proteins were increased by the upregulation of miR-193b, and decreased by its inhibition. *P<0.05 and **P<0.01 vs. the untreated group. miR, microRNA; NC, negative control; MMP, matrix metalloproteinase.