Table I.

List of the top GO terms and KEGG pathways in DEGs.

A, GO biological process
Term	Gene count	P-Value	FDR
GO:0007586 digestion	15	1.17×10−07	2.08×10−04
GO:0010951 negative regulation of endopeptidase activity	17	2.12×10−05	3.70×10−02
GO:0002027 regulation of heart rate	9	3.20×10−05	5.70×10−02
GO:1903779 regulation of cardiac conduction	11	5.77×10−05	1.02×10−01
GO:0006936 muscle contraction	15	7.72×10−05	1.37×10−01
B, Cellular component
Term	Gene count	P-Value	FDR
GO:0005615 extracellular space	136	3.61×10−24	4.97×10−21
GO:0005576 extracellular region	149	8.50×10−23	1.17×10−19
GO:0030018 Z disc	23	1.44×10−09	1.99×10−06
GO:0072562 blood microparticle	24	3.90×10−08	5.37×10−05
GO:0043204 perikaryon	17	4.67×10−06	6.00×10−03
C, GO molecular function
Term	Gene count	P-Value	FDR
GO:0005198 structural molecule activity	37	5.61×10−12	8.54×10−09
GO:0008201 heparin binding	24	5.09×10−08	7.74×10−05
GO:0005179 hormone activity	18	9.67×10−08	1.47×10−04
GO:0008307 structural constituent of muscle	9	1.71×10−04	2.60×10−01
GO:0005102 receptor binding	29	2.54×10−04	3.85×10−01
D, KEGG analysis
Pathway	Gene count	P-Value	FDR
hsa04080:Neuroactive ligand-receptor interaction	28	4.48×10−06	6.00×10−03
hsa04970:Salivary secretion	14	1.67×10−05	2.10×10−02
hsa04971:Gastric acid secretion	10	1.50×10−03	1.96
hsa04972:Pancreatic secretion	11	2.50×10−03	3.11
hsa04610:Complement and coagulation cascades	9	4.10×10−03	5.15

GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; FDR, false discovery rate.