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Jatrorrhizine forms a stable complex with NorA. (A) The hydrophobic interaction between jatrorrhizine and the hydrophobic cleft of NorA. (B) Interactions are demonstrated between jatrorrhizine and amino acid residues (hydrogen bonds) or polar groups (electrostatic interaction). Interactions: Hydrophobic interaction (green), hydrogen bond (light green) and electrostatic interaction (orange). NorA, NorA multidrug efflux pump.
