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A combination of NFX and jatrorrhizine reduced the growth of MRSA SA1199B after 24 h in neutropenic mice models. A total of 10 mice were intramuscularly infected with MRSA strain SA1199B. After 1 h the animals were treated with PBS, jatrorrhizine, NFX, combination of jatrorrhizine and NFX or oflaxacin. Thigh samples were collected after 24 h. **P<0.01, ***P<0.001 vs. PBS. MRSA, methicillin-resistant Staphylococcus aureus; NFX, norfloxacin.
