Table 1.
Characteristic Or Measure | Healthy Controls | MDD Patients | t-test or χ2 test (MDD Patients vs Healthy Controls) |
---|---|---|---|
Age (years; mean ± S.D.) | 44.6 ± 11.2 | 46.0 ± 10.2 | n.s. |
Sex (men : women) | 206 : 144 | 46 : 36 | n.s. |
Years of education | 14.5 ± 1.8 | 13.7 ± 2.4 | p < 0.01 |
Employment status (employed : nonemployed) | 346: 4 | 48: 34 | p < 0.001 |
Marital status (single : married) | 90 : 257 | 36 : 46 | p = 0.001 |
Living alone (yes : no) | 59: 291 | 27 : 55 | p = 0.001 |
Offspring (yes : no) | 247: 103 | 45 : 37 | p = 0.006 |
Number of offspring (mean ± S.D.) | 1.5 ± 1.2 | 1.0 ± 1.0 | p < 0.001 |
Comorbid physical disease (yes : no) | 111: 239 | 33 : 49 | n.s. |
Comorbid psychiatric disorder (yes : no) | 0: 350 | 13: 69 | p < 0.001 |
First-degree relative with mood disorder (yes : no) | 26: 324 | 9: 73 | n.s. |
First-degree relative with MDD (yes : no) | 21: 329 | 7: 75 | n.s. |
PHQ-9 score | 2.8 ± 2.6 | 15.5 ± 7.1 | p < 0.001 |
Neuroticism score (from EPQ-R) | 3.5 ± 3.1 | 7.8 ± 3.0 | p < 0.001 |
Victimization score | 2.0 ± 3.2 | 4.4 ± 3.8 | p < 0.001 |
Notes: Values represent number or mean ± standard deviation (SD).
Abbreviations: S.D., standard deviation; MDD, major depressive disorder; EPQ-R, Eysenck Personality Questionnaire-revised; PHQ-9, Patient Health Questionnaire-9; n.s., not significant.