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. 2019 Sep 23;11(18):7847–7858. doi: 10.18632/aging.102293

Table 3. General clinical characteristics of the obese and non-obese cohorts.

Characteristic Obese subjects (n=584) Non-obese subjects (n=1104) P Obese subjects Non-obese subjects
NAFLD (n=202) Non-NAFLD (n=382) P NAFLD (n=343) Non-NAFLD (n=761) P
Age, years 42.39±12.60 42.22±12.52 <0.001 44.76±31.13 44.83±12.96 0.559 40.35±11.87 40.83±12.19 0.516
Male/female 218/327 487/656 <0.001 106/96 223/159 0.142 127/216 256/505 0.554
BMI, kg/m2 24.11±3.51 23.99±3.33 <0.001 27.56±2.49 27.56±2.35 0.736 21.97±2.01 22.12±1.97 0.224
ALT, U/L 23.78±17.59 23.67±25.52 <0.001 31.34±22.65 31.01±36.84 0.200 19.23±11.82 19.97±16.26 0.625
AST, U/L 25.18±14.51 21.25±9.72 <0.001 35.39±11.68 25.06±15.81 0.052 20.54±5.99 21.56±10.97 0.296
γ-GT, U/L 24.95±20.91 25.46±27.33 <0.001 31.79±23.68 35.46±36.72 0.635 20.54±17.49 20.48±19.48 0.933
Serum triglyceride, mmol/L 1.39±1.11 1.31±1.03 <0.001 1.74±1.29 1.68±1.43 0.587 1.68±0.91 1.13±0.68 0.479
Serum total cholesterol, mmol/L 4.90±1.01 4.87±1.00 <0.001 5.05±1.06 6.52±1.48 0.838 4.81±0.98 4.80±0.93 0.790
Serum LDL-C, mmol/L 2.85±0.67 2.84±0.69 <0.001 3.01±0.70 2.99±0.68 0.895 2.75±0.62 2.77±0.66 0.608
Fasting plasma glucose, mmol/L 5.32±1.06 5.34±1.03 <0.001 5.58±1.16 5.70±1.41 0.510 5.17±1.00 5.15±0.71 0.278
Serum FGF21, pg/ml 293.07±258.03 303.42±291.79 <0.001 361.35±306.29 366.63±311.56 0.924 244.70±205.25 267.57±269.94 0.605

Data are means±SD or counts. P: level of statistical significance with the Kruscal-Wallis non-parametric test.