Table 8. Associations between SNPs and NAFLD in the obese group.
Gene | SNP | Minor allele | Dominate model | Additive model | |||||
OR (95%CI) | SE | P | OR (95%CI) | SE | P | ||||
KLB | rs7670903 | A | 1.03 (0.69,1.53) | 0.20 | 0.881 | 0.98 (0.75,1.27) | 0.13 | 0.862 | |
KLB | rs7674434 | G | 1.89 (1.22,2.93) | 0.22 | 0.004 | 1.78 (1.19,2.67) | 0.21 | 0.005 | |
KLB | rs12152703 | T | 1.86 (1.20,2.88) | 0.22 | 0.006 | 1.75 (1.16,2.63) | 0.21 | 0.007 | |
KLB | rs2608819 | T | 1.30 (0.88,1.22) | 0.20 | 0.191 | 1.28 (0.91,1.82) | 0.18 | 0.160 | |
FGF21 | rs499765 | G | 1.12 (0.76,1.63) | 0.19 | 0.572 | 1.14 (0.89,1.46) | 0.13 | 0.302 | |
FUT1 | rs838136 | C | 0.69 (0.47,0.99) | 0.19 | 0.045 | 0.82 (0.64,1.06) | 0.13 | 0.135 | |
FGFR1 | rs4733946 | T | 1.10 (0.72,1.69) | 0.22 | 0.647 | 1.10 (0.75,1.61) | 0.19 | 0.624 | |
FGFR2 | rs3135761 | A | 1.03 (0.70,1.52) | 0.20 | 0.87 | 1.06 (0.83,1.35) | 0.12 | 0.631 |
Abbreviations: OR: odds ratio, 95%CI: 95% confidence interval, SE: standard error, P: level of statistical significance of the difference between the obesity cases and controls.
Dominate model: Dominate model covariate adjusted association analysis, adjusted for age (years) and sex.
Additive model: Additive model covariate adjusted association analysis, adjusted for age (years) and sex.