Table 1. LPCAT1 immunostaining and breast cancer phenotype.
LPCAT1 IHC result (%) | P | |||||
N | Negative | Weak | Moderate | Strong | ||
All cancers | 1774 | 8.7 | 48.1 | 28.7 | 14.4 | |
Histology | <0.0001 | |||||
No special type (NST) | 1277 | 7.8 | 46.0 | 30.0 | 16.2 | |
Lobular carcinoma | 228 | 11.4 | 62.7 | 20.2 | 5.7 | |
Medullary carcinoma | 60 | 6.7 | 35.0 | 40.0 | 18.3 | |
Cribriform carcinoma | 53 | 22.6 | 50.9 | 18.9 | 7.5 | |
Tubular carcinoma | 38 | 18.4 | 57.9 | 23.7 | 0.0 | |
Papillary carcinoma | 27 | 11.1 | 37.0 | 33.3 | 18.5 | |
Mucinous carcinoma | 50 | 2.0 | 54.0 | 34.0 | 10.0 | |
Other and rare types* | 41 | 4.9 | 39.0 | 29.3 | 26.8 | |
Tumor stage | 0.0176 | |||||
pT1 | 638 | 9.2 | 52.2 | 27.9 | 10.7 | |
pT2 | 856 | 7.9 | 46.6 | 28.6 | 16.8 | |
pT3 | 101 | 10.9 | 47.5 | 22.8 | 18.8 | |
pT4 | 202 | 8.4 | 42.6 | 34.2 | 14.9 | |
Nodal status | 0.2865 | |||||
pN0 | 768 | 9.0 | 50.0 | 28.0 | 13.0 | |
pN1 | 656 | 8.2 | 47.7 | 29.3 | 14.8 | |
pN2 | 102 | 9.8 | 37.3 | 33.3 | 19.6 | |
BRE grade | <0.0001 | |||||
1 | 415 | 14.5 | 59.8 | 22.2 | 3.6 | |
2 | 668 | 7.8 | 54.2 | 27.4 | 10.6 | |
3 | 570 | 4.7 | 35.4 | 34.4 | 25.4 | |
ER status | <0.0001 | |||||
Negative | 406 | 5.9 | 32.0 | 33.3 | 28.8 | |
Positive | 1289 | 9.7 | 52.8 | 27.2 | 10.3 | |
PR status | <0.0001 | |||||
Negative | 1056 | 8.7 | 45.9 | 27.7 | 17.7 | |
Positive | 567 | 9.2 | 52.2 | 29.5 | 9.2 | |
HER2 status | <0.0001 | |||||
Normal | 1153 | 9.1 | 51.2 | 28.4 | 11.3 | |
Amplified | 245 | 5.7 | 31.4 | 29.0 | 33.9 |
*including carcinoma with apocrine differentiation and metaplastic carcinoma of no special type.