Table 1. Correlation between miR-375-3p expression and clinicopathological variables of CRC patients (n=130).
Variables | miR-375-3p expression | P-value1 | ||
Total (n=130) | High (n=65) | Low (n=65) | ||
Age (years) | ||||
≤60 | 58 | 30 | 28 | 0.724 |
>60 | 72 | 35 | 37 | |
Gender | ||||
Male | 63 | 33 | 30 | 0.599 |
Female | 67 | 32 | 35 | |
Tumor size (cm) | ||||
≤5 | 89 | 50 | 39 | 0.038 |
> 5 | 41 | 15 | 26 | |
Tumor invasion depth | ||||
T1-2 | 101 | 56 | 45 | 0.020 |
T3-4 | 29 | 9 | 20 | |
Lymph node metastasis | ||||
N0 | 50 | 30 | 20 | 0.071 |
N1-2 | 80 | 35 | 45 | |
Distant metastasis | ||||
M0 | 74 | 42 | 32 | 0.076 |
M1-2 | 56 | 23 | 33 | |
TNM stage | ||||
I–II | 97 | 56 | 41 | 0.002 |
III–IV | 33 | 9 | 24 |
1Statistical significant results (in bold).