Table 2. Univariate and multivariate analysis of clinicopathological parameters for overall survival in 130 CRC patients.
| Variables | Univariate analysis | Multivariate analysis | ||
| HR (95%CI) | P-value1 | HR (95%CI) | P-value1 | |
| miR-375-3p expression (high vs low) | 2.48 (1.52-4.05) | <0.001 | 2.54 (1.18-4.33) | 0.001 |
| Tumor size (≤5cm vs >5cm) | 1.28 (0.67-2.51) | 0.109 | ||
| Tumor invasion depth (T1/2 vs T3/4) | 1.31 (1.15-2.91) | 0.034 | 1.02(0.85-1.79) | 0.548 |
| TNM stage (I/II vs III/IV) | 3.69 (2.32-7.87) | <0.001 | 3.35 (1.64-8.03) | 0.001 |
| Lymph node metastasis (N0 vs N1/2) | 0.99 (0.72-1.56) | 0.253 | ||
| Distant metastasis (M0 vs M1/2) | 2.04 (0.95-4.52) | 0.086 | ||
| Age (≤60 vs >60) | 0.64 (0.48-1.34) | 0.883 | ||
| Gender (male vs female) | 0.42 (0.35-1.26) | 0.562 | ||
1Statistical significant results (in bold)
Abbreviations: CI, confidence interval; HR, hazard ratio.